BookBairong Shen, Haixu Tang, Xiaoqian Jiang, editors.
Summary: "This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level -- e.g. different omics data at the molecular level -- but also data from different levels -- the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics"--Publisher's description.
Contents:
NGS for sequence variants / Shaolei Teng
RNA bioinformatics for precision medicine / Jiajia Chen, Bairong Shen
Exploring human diseases and biological mechanisms by protein structure prediction and modeling / Juexin Wang, Joseph Luttrell IV, Ning Zhang, Saad Khan, NianQing Shi, Michael X. Wang [and others]
Computational methods in mass spectrometry-based proteomics / Sujun Li, Haixu Tang
Informatics for metabolomics / Kanthida Kusonmano, Wanwipa Vongsangnak, Pramote Chumnanpuen
Metagenomics and single-cell omics data analysis for human microbiome research / Maozhen Han, Pengshuo Yang, Hao Zhou, Hongjun Li, Kang Ning
Text mining for precision medicine: bringing structure to EHRs and biomedical literature to understand genes and health / Michael Simmons, Ayush Singhal, Zhiyong Lu
Medical imaging informatics / William Hsu Ph.D, Suzie El-Saden, Ricky K. Taira
LIMS and clinical data management / Yalan Chen, Yuxin Lin, Xuye Yuan, Bairong Shen
Biobanks and their clinical application and informatics challenges / Lan Yang, Yalan Chen, Chunjiang Yu, Bairong Shen
XML, ontologies, and their clinical applications / Chunjiang Yu, Bairong Shen
Bayesian computation methods for inferring regulatory network models using biomedical data / Tianhai Tian
Network-based biomedical data analysis / Yuxin Lin, Xuye Yuan, Bairong Shen.
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