BookRicardo Jorge Gelpi, Alberto Boveris, Juan José Poderoso, editors.
Contents:
Introduction
Section 1 GENERAL ASPECTS: 1 The concept of oxidative stress after 30 years
2 Evolution of atmospheric oxygen and oxygen metabolism
3 Mitochondria as origin of cellular oxidative stress
4 Biochemistry and physiology of mtNOS
5 Biochemistry of nitrogen reactive species
6 Biochemistry of nitro fatty acids
7 Mammalian adaptation to life at high altitude
8 Metabolic syndrome and oxidative stress in rat pancreas
9 Progesterone prevents mitochondrial dysfunction and oxidative stress in the spinal cord of wobbler mice
10 Mitochondrial transfer by intercellular nanotubes
Section 2 CARDIOVASCULAR: 11 Role of Oxidative Stress in Subcellular Defects in Ischemic Heart Disease
12 Regulation of protein nitrosylation by Trx1
13 Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protection
14 Antioxidant supplementation in elderly cardiovascular patients
15 Rupture of redox homeostasis in a model of pulmonary artery
16 Mitochondrial reactive oxygen species triggered by the cardiac renin-angiotensin-aldosterone system
17 Mitochondrial complex I inactivation and increased autooxidation after ischemia-reperfusion in the stunned heart
18 Oxidized LDL and atherogenesis
19 Reactive oxygen species and cyclooxygenase products in the regulation of blood flow in small vessels
20 Thioredoxin-1 attenuates postischemic ventricular and mitochondrial dysfunctions
21 Nitro-arachidonic acid reduces the damaged area in rat myocardial infarction
22 Inhaled particulate matter and myocardial dysfunction
Section 3 NEURODEGENERATION AND NEURONAL FUNCTION: 23 Effect of lipoic acid in the triple transgenic mouse model of Alzhaimer's disease
24 Neurovascular coupling mediated by NO in the hippocampus
25 Protection from neurodegeneration: signaling and mitocondrial regulation
26 Oxidative stress and neurodegeneration
27 Oxidative stress, metabolic syndrome and Alzheimerþs disease
28 Systemic oxidative stress in patients with neurodegenerative diseases
Section 4 CANCER: 29 Oxygen metabolism and oxidative stress in cancer cells
30 Mitochondrial biogenesis is required for survival and propagation of cancer cells
31 Tumor immunology & immunotherapy in patients
32 Oncogene-induced Nrf2 repression as adaptive response of cancer cells to acquire a pro-oxidant state favoring cell survival and in vivo tumor growth
33 Mitochondrial dynamics regulate oxidative metabolism in Leydig tumor cells
Index.