BookDonald E. Mager, Holly H.C. Kimko, editors.
Contents:
Role of Systems Modeling in Regulatory Drug Approval
Quantitative Systems Pharmacology: Applications and Adoption in Drug Development
Systems Pharmacology: An Overview
Discrete dynamic modeling: a network approach for systems pharmacology
Kinetic Models of Biochemical Signaling Networks
Mechanistic Models of Physiological Control Systems
Foundations of Pharmacodynamic Systems Analysis
Direct, Indirect, and Signal Transduction Response Modeling
Irreversible Pharmacodynamics
Feedback Control Indirect Response Models
Nonlinear Mixed Effects Modeling in Systems Pharmacology
Detecting Pharmacokinetic and Pharmacodynamic Covariates From High-Dimensional Data
Multi-Scale Modeling of Drug Action in the Nervous System
Mechanistic Modeling of Inflammation
Systems Pharmacology of Tyrosine Kinase Inhibitor-Associated Toxicities
Translational Modeling of Antibacterial Agents
Viral Dynamic Modeling of Hepatitis C Virus Infection: Past Successes and Future Challenges
Using Systems Pharmacology to Advance Oncology Drug Development
Systems Pharmacology Modeling in Type 2 Diabetes Mellitus.