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  • Book
    Ellen B. Fung, Laura K. Bachrach, Aenor J. Sawyer, editors.
    Contents:
    1. Rationale for bone health assessment in childhood and adolescence
    2. Tools for measuring bone in children and adolescents
    3. Dual-energy X-Ray absorptiomery technology
    4. Indications for DXA in children and adolescents
    5. Acquisition of DXA in children and adolescents
    6. Analysis and evaluation of DXA in children and adolescents
    7. Reporting DXA results for children and adolescents
    8. DXA evaluation of infants and toddlers
    9. DXA in children with special needs
    10. Bone mineral density as a predictor of vertebral fractures in children and adolescents
    11. Lessons learned from clinical research using QCT, pQCT, and HR-pQCT
    12. Evaluation of fracture without known trauma: use of DXA in differential diagnosis
    13. What's next in the field of bone health in pediatrics? Research considerations
    Appendix A
    Appendix B
    Appendix C
    Appendix D
    Index.
    Digital Access Springer 2016
  • Article
    Munster AM, Loadholdt CB, Leary AG, Barnes MA.
    Surgery. 1977 Jun;81(6):692-5.
    Normal human lymphocytes in culture were stimulated by the addition of phytohemagglutinin, and deoxyribonucleic acid (DNA) synthesis was measured by the incorporation of tritiated thymidine. The effect of 11 commonly used antibiotics on DNA synthesis then was measured by adding each antibiotic to the culture in concentrations ranging from 2 to 64 microng/ml, a range which covers the plasma levels obtained during customary clinical therapy. Severe dose-dependent suppression of DNA synthesis was found in the presence of two preparations of minocycline, oxytetracycline, and the ascorbic acid salt of tetracycline. Less severe but stil significant suppression was found in the presence of chloramphenicol, clindamycin, tetracycline, and ascorbic acid alone. No effect was noted when penicillin, carbenicillin, or cephalothin was added, and slight stimulation was found in the presence of gentamicin. It is postulated that these findings may help to explain fungal and viral superinfection following antibiotic therapy and that they may play a role in the failure of antibiotic therapy to eliminate some infections.
    Digital Access Access Options