Bookedited by Toshio Nakanishi, Roger R. Markwald, H.Scott Baldwin, Bradley B. Keller, Deepack Srivastava, Hiroyuki Yamagishi.
Contents:
Part I. From Molecular Mechanism to Intervention for Congenital Heart Diseases, Now and Future
Reprogramming Approaches to Cardiovascular Disease: From Developmental Biology to Regenerative Medicine
The arterial epicardium, a developmental approach to cardiac disease and repair
Cell sheet tissue engineering for heart failure
Future treatment of heart failure and pathophysiological analysis of various heart diseases using human iPS cell-derived cardiomyocytes
Congenital heart disease: in search of remedial etiologies
Part II. Left-Right Axis and Heterotaxy Syndrome
Left-right Asymmetry and Human Heterotaxy Syndrome
Roles of motile and immotile cilia in left-right symmetry breaking
Role of cilia and left-right patterning in congenital heart disease
Pulmonary arterial hypertension in patients with heterotaxy /polysplenia syndrome
Part III. Cardiomyocyte and Myocardial Development
Single Cell Expression Analyses of Embryonic Cardiac Progenitor Cells
Meis1 Regulates Post-Natal Cardiomyocyte Cell Cycle Arrest
Intercellular signalling in cardiac development and disease: NOTCH
The epicardium in ventricular septation during evolution and development
S1P-S1p2 signaling in cardiac precursor cells migration
Myogenic progenitor cell differentiation is dependent on modulation of mitochondrial biogenesis through autophagy
The role of the thyroid in the developing heart
Part IV. Valve Development and Diseases
Atrioventricular valve abnormalities: From molecular mechanisms underlying morphogenesis to clinical perspective
Molecular Mechanisms of Heart Valve Development and Disease
A novel role for endocardium in perinatal valve development: Lessons learned from tissue specific gene deletion of the Tie1 receptor tyrosine kinase
The Role of the Epicardium in the Formation of the Cardiac Valves in the Mouse
TMEM100, a novel intracellular transmembrane protein essential for vascular development and cardiac morphogenesis
Cell autonomous regulation of BMP-2 in endocardial cushion cells during AV valvuloseptal morphogenesis
Part V. The Second Heart Field and Outflow Tract
Properties of cardiac progenitor cells in the second heart field
Nodal signaling and congenital heart defects
Utilizing Zebrafish to Understand Second Heart Field Development
A history and interaction of outflow progenitor cells implicated in "Takao syndrome"
The loss of Foxc2 expression in the outflow tract links the interrupted arch in the conditional Foxc2 knockout mouse
Environmental modification for phenotype of truncus arteriosus in Tbx1 hypomorphic mice
Part VI. Vascular Development and Diseases
Extracellular matrix remodeling in vascular development and disease
The "cardiac neural crest" concept revisited
Roles of endothelial Hrt genes for vascular development
Placental Expression of Type 1 and 3 Inositol Trisphosphate Receptors is Required for the Extra-embryonic Vascular Development
Tissue Remodeling in Vascular Wall in Kawasaki Disease-related Vasculitis Model Mice
Part VII. Ductus Arteriosus
Progerin expression during normal closure of the human ductus arteriosus: A case of premature ageing?
The multiple roles of prostaglandin E2 in the regulation of the ductus arteriosus
Developmental Differences in the Maturation of Sarcoplasmic Reticulum and Contractile Proteins in Large Blood Vessels Influences Their Contractility
Fetal and Neonatal Ductus Arteriosus is Regulated with ATP-sensitive Potassium Channel
Part VIII. Conduction System and Arrhythmia
Regulation of vertebrate conduction system development
Cardiac Pacemaker Development from a Tertiary Heart Field
Endothelin receptor type A expressing cell population in the inflow tract contributes to chamber formation
Specific isolation of HCN4 positive cardiac pace-making cells derived from embryonic stem cell
Part IX. Current Molecular Mechanism in Cardiovascular Development
Combinatorial functions of transcription factors and epigenetic factors in heart development and disease
Pcgf5 contributes to PRC1 (Polycomb repressive complex 1) in developing cardiac cells
non-coding RNAs in cardiovascular disease
Part X. iPS Cells and Regeneration in Congenital Heart Diseases
Human pluripotent stem cells to model congenital heart disease
Engineered cardiac tissues generated from immature cardiac and stem-cell derived cells: Multiple approaches and outcomes
Dissecting the left heart hypoplasia by pluripotent stem cells
Lentiviral gene transfer to iPS cells; toward the cardiomyocyte differentiation of Pompe disease-specific iPS cells
Molecular analysis of long-term cultured cardiac stem cells for cardiac regeneration
Epicardial contribution in neonatal heart regeneration
Part XI. Current Genetics in Congenital Heart Diseases
Genetic discovery for congenital heart defects
Evidence that deletion of ETS-1, a gene in the Jacobsen syndrome (11q-) cardiac critical region, causes congenital heart defects through impaired cardiac neural crest cell function
Notch signaling in aortic valve development and disease
To detect and explore mechanism of CITED2 mutation and methylation in children with congenital heart disease.