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  • Book
    edited by Dieter Steinhilber, editor.
    Summary: Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.

    Contents:
    Introduction into lipoxygenases
    5-Lipoxygenase
    Leukotriene A4 hydrolase and LTC4 synthase
    Catalytic multiplicity of 15-lipoxygenase-1 orthologs (ALOX15) of different species
    Platelets and lipoxygenases
    Lipoxygenases and cardiovascular diseases
    Role of lipoxygenases in pathogenesis of cancer
    The physiology and pathophysiology of lipoxygenases in the skin
    5-Oxo-ETE and inflammation
    Lipoxins, resolvins, and the resolution of inflammation.
    Digital Access Springer 2016
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    2016
    QP603.L56 L57 2016
    1