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  • Book
    Shein-Chung Chow, Jen-Pei Liu.
    Digital : Wiley2014
    pt. I. Introduction -- Basic statistical concepts -- Basic design considerations -- Randomization and blinding -- pt. II. Designs and their classifications -- Designs for clinical trials -- Designs for cancer clinical trials -- Classification of clinical trials -- pt. III. Analysis of clinical data -- Analysis of continuous data -- Analysis of categorical data -- Censored data and interim analysis -- Sample size determination -- pt. IV. Issues in evaluation -- Issues in efficacy evaluation -- Safety assessment -- pt. V. Recent development -- Biomarkers and targeted clinical trials -- Trials for evaluating accuracy of diagnostic devices -- Statistical methods in translational medicine -- Adaptive clinical trial designs -- Traditional Chinese medicine -- pt. VI. Conduct of clinical trials -- Preparation and implementation of a clinical protocol -- Data management of a clinical trial.