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  • Book
    Shein-Chung Chow, Jen-Pei Liu.
    Contents:
    pt. I. Introduction
    Basic statistical concepts
    Basic design considerations
    Randomization and blinding
    pt. II. Designs and their classifications
    Designs for clinical trials
    Designs for cancer clinical trials
    Classification of clinical trials
    pt. III. Analysis of clinical data
    Analysis of continuous data
    Analysis of categorical data
    Censored data and interim analysis
    Sample size determination
    pt. IV. Issues in evaluation
    Issues in efficacy evaluation
    Safety assessment
    pt. V. Recent development
    Biomarkers and targeted clinical trials
    Trials for evaluating accuracy of diagnostic devices
    Statistical methods in translational medicine
    Adaptive clinical trial designs
    Traditional Chinese medicine
    pt. VI. Conduct of clinical trials
    Preparation and implementation of a clinical protocol
    Data management of a clinical trial.
    Digital Access Wiley 2014