BookRodney J.Y. Ho, Milo Gibaldi.
Contents:
Introduction to biopharmaceuticals
Distinctions of biologic versus small molecule platforms in drug development
Financing biologic drug development
Application of biotechnology in drug discovery and early development
Large-scale production of recombinant proteins
Clinical pharmacology, toxicology, and therapeutic dosage & response
Clinical evaluation and regulatory approval & enforcement of biopharmaceuticals
Pharmacoeconomics and drug pricing / Garrison
Antibodies and derivatives
Hematopoietic growth and coagulation factors
Cytokines and interferons
Hormones
Enzymes
Vaccines / Hu, Ho
Other biopharmaceutical products
Advances in personalized medicine : pharmacogenetics in drug therapy
Gene and cell therapy
Pharmacoeconomics, outcome, and health technology assessment research in drug development
Summary and future prospects.