Chapter 1. Uncertainty in clinical medicine -- Chapter 2. The logic of medicine -- Chapter 3. Probability: uncertainty quantified -- Chapter 4. Decision making: making choices -- Chapter 5. Solving unstructured problems -- Chapter 6. Therapeutic decision making -- Chapter 7. Evidence-based medicine -- Chapter 8. Improving the quality of care -- Chapter 9. Common fallacies -- Chapter 10. Putting this book into practice -- Appendix 1. More on probability curves -- Appendix 2. More on likelihood ratios -- Appendix 3. The minimum Bayes factor and likelihood ratios.