Bookedited by Juan I. Castrillo, Stephen G. Oliver.
Contents:
Alzheimer's as a systems-level disease involving the interplay of multiple cellular networks / Juan I. Castrillo and Stephen G. Oliver
Application of systems theory in longitudinal studies on the origin and progression of Alzheimer's disease / Simone Lista [and others]
APP proteolytic system and its interactions with dynamic networks in Alzheimer's disease / Sally Hunter, Steven Martin, and Carol Brayne
Effects of mild and severe oxidative stress on BACE1 expression and APP amyloidogenic processing / Jiangli Tan, Qiao-Xin Li, and Genevieve Evin
Advanced assay monitoring APP-carboxyl-terminal fragments as markers of APP processing in Alzheimer disease mouse models / Ana García-Osta and Mar Cuadrado-Tejedor
Optical super-resolution imaging of [beta]-amyloid aggregation in vitro and in vivo : method and techniques / Dorothea Pinotsi, Gabriele S. Kaminski Schierle, and Clemens F. Kaminski
Protocols for monitoring the development of Tau pathology in Alzheimer's disease / Alberto Rábano [and others]
LC3-II tagging and western blotting for monitoring autophagic activity in mammalian cells / Anne Streeter, Fiona M. Menzies, and David C. Rubinsztein
Advanced mitochondrial respiration assay for evaluation of mitochondrial dysfunction in Alzheimer's disease / Amandine Grimm, Karen Schmitt, and Anne Eckert
Analysis of microglial proliferation in Alzheimer's disease / Diego Gomez-Nicola and V. Hugh Perry
Yeast as a model for Alzheimer's disease : latest studies and advanced strategies / Mathias Verduyckt [and others]
Yeast as a model for studies on A[beta] aggregation toxicity in Alzheimer's disease, autophagic responses, and drug screening / Afsaneh Porzoor and Ian Macreadie
Drosophila melanogaster as a model for studies on the early stages of Alzheimer's disease / Jung Yeon Lim, Stanislav Ott, and Damian C. Crowther
Chronic mild stress assay leading to early onset and propagation of Alzheimer's disease phenotype in mouse models / Mar Cuadrado-Tejedor and Ana García-Osta
Gene expression studies on human trisomy 21 iPSCs and neurons : towards mechanisms underlying Down's syndrome and early Alzheimer's disease-like pathologies / Jason P. Weick, Huining Kang, George F. Bonadurer III, and Anita Bhattacharyya
Cortical differentiation of human pluripotent cells for in vitro modeling of Alzheimer's disease / Nathalie G. Saurat, Frederick J. Livesey, and Steven Moore
Next generation sequencing in Alzheimer's disease / Lars Bertram
Pooled-DNA sequencing for elucidating new genomic risk factors, rare variants underlying Alzheimer's disease / Sheng Chih Jin, Bruno A. Benitez, Yuetiva Deming, and Carlos Cruchaga
New genome-wide methods for elucidation of candidate copy number variations (CNVs) contributing to Alzheimer's disease heritability / Kinga Szigeti
RNA-sequencing to elucidate early patterns of dysregulation underlying the onset of Alzheimer's disease / Bei Jun Chen, James D. Mills, Caroline Janitz, and Michael Janitz
Systems biology approaches to the study of biological networks underlying Alzheimer's disease : role of miRNAs / Wera Roth, David Hecker, and Eugenio Fava
Emerging role of metalloproteomics in Alzheimer's disease research / Dominic J. Hare, Alan Rembach, and Blaine R. Roberts
Redox proteomics in human biofluids : sample preparation, separation and immunochemical tagging for analysis of protein oxidation / Fabio Di Domenico, Marzia Perluigi, and D. Allan Butterfield
Advanced shotgun lipidomics for characterization of altered lipid patterns in neurodegenerative diseases and brain injury / Miao Wang and Xianlin Han
AlzPathway, an updated map of curated signaling pathways : towards deciphering Alzheimer's disease pathogenesis / Soichi Ogishima [and others]
Computational network biology approach to uncover novel genes related to Alzheimer's disease / Andreas Zanzoni
Network approaches to the understanding of Alzheimer's disease : from model organisms to humans / Justin Yerbury, Dan Bean, and Giorgio Favrin
Characterization of genetic networks associated with Alzheimer's disease / Bin Zhang, Linh Tran, Valur Emilsson, and Jun Zhu
Network-based analysis for uncovering mechanisms underlying Alzheimer's disease / Masataka Kikuchi [and others]
SDREM method for reconstructing signaling and regulatory response networks : applications for studying disease progression / Anthony Gitter and Ziv Bar-Joseph
Advanced neuroimaging methods towards characterization of early stages of Alzheimer's disease / Jorge Sepulcre and Joseph C. Masdeu
Plasma proteomics biomarkers in Alzheimer's disease : latest advances and challenges / Robert Perneczky and Liang-Hao Guo
Practical guide for exploring opportunities of repurposing drugs for CNS diseases in systems biology / Hongkang Mei [and others].