BookFernando D. Dip, Takeaki Ishizawa, Norihiro Kokudo, Raul J. Rosenthal, editors.
Summary: This volume presents the experiences of leading researchers and surgeons with different fluorescence methods. Chapters range from basic science of fluorescence to current clinical applications and new horizons. The first few chapters cover the historical evolution and physical principles of fluorescence and provide the foundation for the reader to understand the current scope and limits of its use in surgery. The second section focuses on the clinical applications of intraoperative fluorescence imaging, including subsections on fluorescence cholangiography, applications to hepatectomy, lymph node navigation, applications to GI tract and pelvic surgery and identification of cancer tissues. The third section focuses on new frontiers including fluorescence probes, imaging systems and applications to photodynamic therapy. Authored by leaders in the development of fluorescent methods worldwide, Fluorescence Imaging for Surgeons: Concepts and Applications will have an impact on numerous medical specialists including general surgeons, colorectal and minimally-invasive surgeons and surgical oncologists. Researchers will find the book to be an invaluable resource on the latest advances in the utilization of nanoparticles and fluorescent probes.
Contents:
Section I: Background
Basic Concepts of Fluorescence and Fluorescent Probes
Past, Present, and Future of Fluorescence
Translation of Therapeutic Antibodies for Intraoperative Fluorescence Imaging
Review of Indocyanine Green Imaging in Surgery
Section II: Imaging Systems
D-Light P System (Karl Storz) (with video)
Robotic Surgery Using Firefly System
Fluorescence Imaging Systems (PDE, HyperEye Medical System, and Prototypes in Japan)
The Pinpoint System
Economic Impact of Fluorescent Cholangiography
Real-time Near-Infrared Fluorescent Cholangiography During Robotic Single-Site Cholecystectomy
Fluorescent Guided Liver Surgery: Paul Brousse Experiences and Perspective
Fluorescence Imaging in Laparoscopic Hepatectomy (with video)
Section III: Clinical Applications of Intraoperative Fluorescence Imaging
Identification of Hepatic Segment (with video)
Intraoperative Evaluation of Regional Portal Uptake Function (with video)
Identification of Hepatocellular Carcinoma (with video)
Identification of Metastatic Liver Cancer (with video)
Prediction for Postoperative Intrahepatic Recurrence of Hepatocellular Carcinoma
Detection of Bile Leakage after Hepatic Resection by Intraoperative Indocyanine Gren Flourescent Imaging
Near-Infrared Laser Photodynamic Therapy for Human Hepatocellular Carcinoma Cell Line Tumor with Indocyanine Green Fluorescene
Photodynamic Diagnosis of Gastric Cancer Using 5-Aminolevulinic Acid (with video)
Applications of ICG Fluorescence Imaging for Surgery in Colorectal Cancer
Fluorophore-Conjugated Chimeric Anti-CEA Antibodies for Fluorescence-Guided Surgery of Gastrointestinal (GI) Tumors
Development of a Non-Blurring, Dual-Imaging (X-ray/Fluorescence) Tissue Marker for Localization of Gastrointestinal Tumors
Sentinel Node Navigation Surgery by Infrared Imaging in Gastric Cancer
A Dual Infrared Ray Imaging System for Sentinel Node Mapping Against Early Gastric Cancer: Absorption and Florescence Methods by Infrared Ray Electronic Endoscopy Combined with Indocyanine Green
Indocyanine Green Fluorescence-Navigated Sentital Node Biopsy Showed Higher Sensitivity than the Conventional Radioisotope or Blue Dye Methods: It May Help to Reduce False-Negative Sentinel Lymph Node Biopsies in Skin Cancer
The Indocyanine Green Method is Equivalent to ther (99m) Tc-Labeled Radiotracer Method for Identifying the Sentinel Node in Breast Cancer: A Concordance and Validation Study
Photodynamic Detection of Lymph Node Metastases in Gastronintestinal Cancer by Using 5-Aminolevulinic Acid
Application of Photodynamic Treatment (with video)
Photodynamic Diagnosis Mediated by 5-Aminolevulinic Acid for Urinary Bladder Cancer (with video)
Real-time Assessment of Intestinal Perfusion by Fluorescence-Based Enhanced Reality
Fluorescent Angiography for Flap Planning and Monitoring in Reconstructive Surgery
Fluorescein-Detection of Myocardial Ischemia in an Experimental Model of Acute Coronary Occlusion
Spatial and Temporal Monitoring of Perfusing with Indocyanine Green Videoangiography in Rat Heart
Ureter Identification Using Methylene Blue and Fluorescein
Chymotrypsin Probe for Real-Time Visualization of Pancreatic Leak.