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  • Book
    Fan Lin, Jeffrey Prichard, editors.
    Summary: In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. ℗ℓ Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures. ℗ℓ Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

    Contents:
    Immunohistochemistry Quality Management and Regulation
    Standardization of Diagnostic Immunohistochemistry
    Automated Immunohistochemistry Overview
    Geisinger Immunohistochemical Antibodies and Staining Protocols
    Immunohistochemistry: A Dako Perspective
    Immunohistochemistry: Ventana Perspective
    Rabbit Monoclonal Antibodies
    Detection of Phosphoproteins and Cancer Pathways
    Overview of Predictive Biomarkers and Integration of IHC into Molecular Pathology
    Tissue Microarray
    Unknown Primary/Undifferentiated Neoplasm
    Exfoliative Cytology and Effusions
    Breast
    Predictive Biomarkers in Breast Cancer: ER, PR and Her-2/neu
    Central Nerve System
    Thyroid, Parathyroid and Adrenal Glands
    Salivary Glands and Head and Neck
    Pleuropulmonary and Mediastinal Neoplasms
    Uterus
    Ovary
    Prostate Gland
    Urinary Bladder and Urachus
    Kidney
    Testis and Paratesticular Tissues
    Pancreas and Ampulla
    Liver, Bile Ducts and Gallbladder
    Upper Gastrointestinal Tract
    Lower Gastrointestinal Tract
    Soft Tissue and Bone Tumors. Lymph Node
    Bone Marrow
    Infectious Diseases
    Skin
    Application of Direct Immunofluorescence for Skin and Mucosal Biopsies: A Practical Review
    Application of Fluorescent in Situ Hybridization (FISH) in Surgical and Cytologic Specimens (Solid Tumors, Hematopoietic Tumors, Urine, Bile Duct Brushing and Bronchoscopy).
    Digital Access Springer 2015