BookFan Lin, Jeffrey Prichard, editors.
Summary: In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. ℗ℓ Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures. ℗ℓ Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.
Contents:
Immunohistochemistry Quality Management and Regulation
Standardization of Diagnostic Immunohistochemistry
Automated Immunohistochemistry Overview
Geisinger Immunohistochemical Antibodies and Staining Protocols
Immunohistochemistry: A Dako Perspective
Immunohistochemistry: Ventana Perspective
Rabbit Monoclonal Antibodies
Detection of Phosphoproteins and Cancer Pathways
Overview of Predictive Biomarkers and Integration of IHC into Molecular Pathology
Tissue Microarray
Unknown Primary/Undifferentiated Neoplasm
Exfoliative Cytology and Effusions
Breast
Predictive Biomarkers in Breast Cancer: ER, PR and Her-2/neu
Central Nerve System
Thyroid, Parathyroid and Adrenal Glands
Salivary Glands and Head and Neck
Pleuropulmonary and Mediastinal Neoplasms
Uterus
Ovary
Prostate Gland
Urinary Bladder and Urachus
Kidney
Testis and Paratesticular Tissues
Pancreas and Ampulla
Liver, Bile Ducts and Gallbladder
Upper Gastrointestinal Tract
Lower Gastrointestinal Tract
Soft Tissue and Bone Tumors. Lymph Node
Bone Marrow
Infectious Diseases
Skin
Application of Direct Immunofluorescence for Skin and Mucosal Biopsies: A Practical Review
Application of Fluorescent in Situ Hybridization (FISH) in Surgical and Cytologic Specimens (Solid Tumors, Hematopoietic Tumors, Urine, Bile Duct Brushing and Bronchoscopy).