Bookedited by Asfar S. Azmi.
Summary: Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets.
Contents:
Epidemiology, Treatment, and Outcome of Pancreatic Cancer
Advances in Primary Cell Culture of Pancreatic Cancer
Multimodal Therapies for Pancreatic Cancer
The Role of Notch Signaling Pathway in the Progression of Pancreatic Cancer
Bioinformatics Analysis of Pancreas Cancer Genome in High-Throughput Genomic Technologies
Statistical Analysis of High-Dimensional Data for Pancreatic Cancer
Gene Expression Profiling in Pancreatic Cancer
Genetic Susceptibility and Risk of Pancreatic Cancer
Proteomics in Pancreatic Cancer Translational Research
Proteomic Differences and Linkages between Chemoresistance and Metastasis of Pancreatic Cancer Using Knowledge-Based Pathway Analysis
RNAi Validation of Pancreatic Cancer Antigens Identified by Cell Surface Proteomics
The Significance of the Feedback Loops between Kras and Ink4a in Pancreatic Cancer
Systems Biology of Pancreatic Cancer Stem Cells
Characterizing the Metabolomic Effects of Pancreatic Cancer
Prioritizing Diagnostic, Prognostic, and Therapeutic MicroRNAs in Pancreatic Cancer: Systems and Network Biology Approaches
Integration of Protein Network Activation Mapping Technology for Personalized Therapy: Implications for Pancreatic Cancer
Computational and Biological Evaluation of Radioiodinated Quinazolinone Prodrug for Targeting Pancreatic Cancer
Systems and Network Pharmacology Strategies for Pancreatic Ductal Adenocarcinoma Therapy: A Resource Review.