BookChristos C. Zouboulis, Andreas D. Katsambas and Albert M. Kligman, editors.
Summary: This book, written by experts from across the world, provides comprehensive coverage of acne and rosacea, focusing in particular on pathogenesis and treatment but also considering clinical aspects, prognostic factors, and impacts on quality of life. Both standard knowledge and important, clinically relevant insights that have emerged over the past decade are presented with the goal of assisting the reader in understanding these diseases and improving treatment outcome. It is explained how high-level research has recently given rise to a variety of new concepts in etiology and treatment, and emerging trends are also discussed. The book is in a reader-friendly format that highlights core messages with a very practical and clinical focus. Pathogenesis and Treatment of Acne and Rosacea will be an indispensable reference for all physicians who care for patients with acne or rosacea and for scientists working in the field.
Contents:
The Sebaceous Gland Through the Centuries: A Difficult Path to Independence
Embryology of the Pilosebaceous Unit
Molecular Aspects of Sebaceous Differentiation
Anatomy of the Sebaceous Gland
Sebum and Sebaceous Lipids
Experimental Models of the Sebaceous Gland
Acne Epidemiology and Socioeconomic Aspects
Acne Pathogenesis: What We Have Learned Over the Years
The Role of Hyperkeratinization
The Role of the Sebaceous Gland
The Role of Bacteria
Inflammation in Acne
A New Concept of Acne Pathogenesis
Acne and Genetics
Acne and Androgens
Acne and Inflammation
Acne and Neuropeptides
Acne and Bacteria
The Acne Biofilm
The Evidence Supporting a Link Between Acne and Nutrition
Acne and Smoking
Antimicrobial Peptides in Acne
Acne and Antimicrobial Lipids
Natural and Artificial Suntanning
Acne and Environmental Pollution (Chloracne)
Myths and Beliefs of Acne Pathogenesis: Diet, Smoking, Hygiene
Understanding Acne as a Chronic Disease
Clinical Aspects of Acne Vulgaris
Clinical Aspects of Acne Fulminans
Childhood Acne
Congenital Adrenal Hyperplasia and Acne in the Male Patients
Adult Acne
Drug-Induced Acne
Body-Builder Acne
Acne Cosmetica
Acne in Persons with Dark Skin
Acne and Heredity
Acne Neonatorum
Serum Androgens
Body Mass Index
Sebum Secretion, Skin Type, and pH
Lipids in Serum and Sebum
The Leeds Acne Grading Technique
Evaluation of Clinical Severity by Acne Grading and Lesion Counting
Modern Technology for Imaging and Evaluation of Acne Lesions
Acne and Congenital Adrenal Hyperplasia
The Acne Genes
Vitamins and the Skin
Urinary Hormone Analysis in Acne
Laboratory Evaluations in Acne
Evidenced-Based Treatment of Acne
The Difficult Acne Patient
Improving Compliance with Acne Therapy
Keratolytic Treatment
Topical Antibiotics
Benzoyl Peroxide
Topical Retinoids
Azelaic Acid
Emerging Acne Treatments
Oral Antibiotics
The Antibiotic Resistance in Acne
Prescribing Oral Isotretinoin: The European Approach
Oral Isotretinoin: The US Approach
Hormonal Therapy for Acne
Less Common Treatments
Risk Factors of Acne Relapse
Acne Maintenance Therapy
Cosmetics and Cleansers in Acne
Chemical Peeling in Acne
Lasers and Phototherapy in Acne
Treatment of Acne Scarring
Concepts of Future Acne Treatment
Acne and Quality of Life
Instruments of Measurement of Quality of Life in Acne
The SAHA Syndrome
The Polycystic Ovary Syndrome and Acne
The SAPHO Syndrome
The PAPA Syndrome
Acne in Transplantation Patients
Rosacea: The State of the Art
The Vascular Concept
Rosacea and Neuropeptides
Rosacea and Demodex folliculorum
The Role of Adenosine Triphosphate in the Pathogenesis of Rosacea: An Explanation for the Mode of Action of Tetracyclines for the Treatment of Rosacea
Standard Grading System for Rosacea
Classical Clinical Presentations of Rosacea
Rhinophyma: A Variation of Rosacea?
Ocular Rosacea
Childhood Rosacea
Differential Diagnosis of Rosacea
A Treatment Strategy for Rosacea
Topical Treatment of Rosacea
Systemic Treatment of Rosacea
Laser and Light Therapy of Rosacea
Nonclassical Treatments
Cosmetics in Rosacea
Treatment of Rhinophyma
The Future of Rosacea Treatment
Impact of Rosacea on Quality of Life.