Bookedited by Christiane Ferran, MD, PhD, Department of Surgery,
... Show More Division of Vascular and Endovascular Surgery, Center for Vascular Biology Research, and The Transplant Insitutue, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Summary: "This book is meant to provide the most current knowledge regarding the mechanisms of action of A20, if its versatile functions and their validation in animal models of human disease and its promise as a diagnostic biomarker and therapeutic target"--Publisher's description.
Contents:
A20: a bipartite ubiquitin editing enzyme with immunoregulatory potential / Ingrid Wertz and Vishva Dixit
The biology of A20-binding inhibitors of NF- [kappa]B activation (ABINs) / Lynn Verstrepen, Isabelle Carpentier and Rudi Beyaert
The Biology of A20-Like Molecules / Karine Enesa and Paul Evans
Anti-viral tetris: modulation of the innate anti-viral immune response by A20 / Meztli Arguello, Suzanne Paz, Christiane Ferran, Herwig P. Moll and John Hiscott
A20 expressing tumors and anticancer drug resistance / Cleide Gonçalves da Silva, Darlan Conterno Minussi, Christiane Ferran and Markus Bredel
Translational studies of A20 in atherosclerosis and cardiovascular disease / Fiona C. McGillicuddy, Herwig P. Moll, Samira Farouk, Scott M. Damrauer, Christiane Ferran and Muredach P. Reilly
A20: a biomarker of allograft outcome: a showcase in kidney transplantation / Gabor Bodonyi-Kovacs, Terry B. Strom and Prabhakar Putheti
A20: an omnipotent protein in the liver: Prometheus myth resolved? / Cleide Gonçalves da Silva, Jesus Revuelta Cervantes, peter Studer and Christiane Ferran
Emerging roles for A20 in islet biology and pathology / Nathan W. Zammit and Shane T. Grey
Single nucleotide polymorphisms at the TNFAIP3/A20 locus and susceptibility/resistance to inflammatory and autoimmune diseases / Alessandra Mele, Jesus Revuelta Cervantes, Victor Chien, David Friedman and Christiane Ferran
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