BookTracey A. Martin, Wen G. Jiang, editors.
Summary: There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells.
Contents:
Molecular aspects of tight junctions / Elaine A. McSherry, Mark B. Owens, and Ann M. Hopkins
Distribution of tight junctions and junctional proteins in the human body / Anna-Maria Tokes ... [et al.]
Methods to study tight junctions / Maria Isabel Larre, Catalina Flores-Maldonado, and Marcelino Cereijido
Enhanced vascular permeability in solid tumors : a promise for anticancer nanomedicine / Sebastien Taurin and Khaled Greish
Tight junctions, junctional adhesion molecules (JAMs), and the blood brain barrier / Klaus Ebnet ... [et al.]
Tight junctions in human urinary bladder cancer / Tracey A. Martin ... [et al.]
Tight junctions in colorectal cancer / Frederic Hollande and Marina Papin
Tight junctions in breast cancer : multifaceted players in tumorigenesis and progression / Yvonne Myal and Anne A.A. Blachard
Regulation of tight junctions for therapeutic advantages / Lorenza Gonzalez-Mariscal, Monica Diaz-Coranguez, and Miguel Quiros
VEGF-mediated effects on brain microvascular endothelial tight junctions and transmigration of breast cancer cells across the blood-brain barrier / Shalom Avraham ... [et al.]
Claudin-5 and cancer metastasis / Claudia Malheiros Coutinho-Camillo, Silvia Vanessa Lourenco, and Fernando Augusto Soares
Signaling pathways regulating endothelial cell-cell junctions as a barrier to tumor cell metastasis / Shigetomo Fukuhara and Naoki Mochizuki
ROCK signalling pathway and tight junctions / Jane Lane, Tracey A. Martin, and Wen G. Jiang.