BookKenzo Uchida, Masaya Nakamura, Hiroshi Ozawa, Shinsuke Katoh editors; Yoshiaka Toyama honory editor.
Summary: Neuroprotection and Regeneration of the Spinal Cord comprehensively covers the most recent research in the field of spinal cord injury. The first part of this book focuses on the latest animal models and clinically oriented work, providing extensive information on morphological factors and, biomechanical analysis, in addition to the mechanism of functional recovery. The book goes on to provide information on clinical relevance introducing analysis of spinal cord injuries using MRI and PET. Edited by renowned experts in the field, this book will provide clinical physicians, basic researchers, and postgraduate students with valuable insight into the cutting-edge research and progress in the field of spinal cord injury, treatment, and repair.
Contents:
Pathologies of Spinal Cord Injury
The Mechanism Behind Functional Recovery After the Incomplete Spinal Cord Injury
Microenvironment Within the Injured Spinal Cord Focusing on IL-6
Autophagy in Spinal Cord Injury: Pathogenic Roles and Therapeutic Implications
The Role of the Endoplasmic Reticulum Stress Response in Neural Apoptosis of the Injured Spinal Cord
Roles of Microglia in Spinal Cord Injury
Pathologies of Chronic Compressive Spinal Cord
Biomechanics of the Spinal Cord and the Pia Mater
Biomechanical Analysis of Compressive Myelopathy: The Influence of Morthometry of the Spinal Cord
Morphologic Change and Glial Response to Unilateral Spinal Cord Compression
Morphological Changes in Anterior Horn Cells, Immunoreactivity to Neurotrophic Factors, and Neuronal Cell Death of Spinal Cord Lesions in the Spinal Hyperostotic Mouse (twy/twy) with Chronic Mechanical Cord Compression
In Vivo Tracing of Neural Tracts in Tiptoe-Walking Yoshimura Mice by Diffusion Tensor Tractography
Microarray Analysis of Expression of Cell Death-Associated Genes in Spinal Cord Cells with Cyclic Tensile Strain
Spinal Kyphosis Causes Demyelination and Neuronal Loss in the Spinal Cord
Neuroprotection
Granulocyte Colony-Stimulating Factor-Mediated Neuroprotective Therapy for Spinal Cord Injury
Recombinant Human Hepatocyte Growth Factor Promotes Functional Recovery After Spinal Cord Injury
The Proteoglycan-Degrading Enzymes Promote Functional Recovery After Spinal Cord Injury: Keratan Sulfate and Chondroitin Sulfate
Targeted Retrograde Gene Delivery into the Injured Spinal Cord Using Recombinant Adenovirus Vector Carrying Neurotrophic Factor Gene
Blockade of Interleukin-6 Effects on Cytokine Profiles and Macrophage Activation After Spinal Cord Injury in Mice
Oxidative Stress as Secondary Injury Mechanism After Mechanical Trauma in the Spinal Cord
Transplantation
Regenerative Medicine for Spinal Cord Injury Utilizing iPS Cells
Transplantation of Neural Stem Cells with Valproate for Spinal Cord Injury
The Effects of Mesenchymal Stem Cell-Transduced Multineurotrophin to Improve Function Following Spinal Cord Injury
Axonal Regeneration Across an Artificial Scaffold Combined with Cell Transplantation Applied to the Transected Spinal Cord
Transplantation of Mesenchymal Stem Cells Derived from Bone Marrow in the Injured Spinal Cord
Vascular Regeneration Therapies for Spinal Cord Injury
Clinical Relevance
Stress Distribution of the Spinal Cord and Clinical Relevance in Cervical Spondylotic Myelopathy
Applications and Limitations of pNF-H, a Novel Biomarker for Spinal Cord Injury: Strategy for the Evaluation of Therapeutic Outcomes
Neuroprotective Therapy Using Granulocyte Colony-Stimulating Factor for Acute Spinal Cord Injury: A Multicenter Prospective Controlled Clinical Trial
Assessment of Injured Spinal Cord Using Diffusion Tensor Tractography
Clinical Significance of 3D-MRI/18F-FDG PET Fusion Imaging of Patients with Cervical Compressive Myelopathy
Visualization of Electrophysiological Activity in the Spinal Cord Using Magnetospinography
Spinal Synaptic Plasticity in Chronic Pain
Evaluation of Pain with Functional Neuroimaging.