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  • Book
    Natalia Maltsev, Andrey Rzhetsky, T. Conrad Gilliam, editors.
    Summary: "Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance"--Publisher's description.

    Contents:
    Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine
    Characterizing Multi-omic Data in Systems Biology
    High-throughput Translational Medicine: Challenges and Solutions
    Computational approaches for human disease gene prediction and ranking
    A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization-- Index.
    Digital Access Springer 2014