BookPierre Hainaut, Magali Olivier, Klas G. Wiman, editors.
Contents:
TP53: Coordinator of the Processes That Underlie the Hallmarks of Cancer / Pierre Hainaut
The Inheritance of p53 / Lukasz F. Grochola, Jorge Zeron-Medina, Emmanouela Repapi, Alexander E. Finlayson and Ying Cai, et al.
p53: Guardian of the Metabolome / Masha V. Poyurovsky and Carol Prives
The p53 Family and Stem Cell Biology / Massimiliano Agostini, Alessandro Rufini, Edward T. W. Bampton, Francesca Bernassola and Gerry Melino, et al.
Mutant p53-Driven Tumorigenesis / Tamara Terzian and Guillermina Lozano
Humanised Mouse Models: Targeting the Murine p53 Locus with Human Sequences / Monica Hollstein and Yang Xu
p53 Models for Mammary Carcinogenesis / Wolfgang Deppert and Genrich Tolstonog
TP53 Somatic Mutations: Prognostic and Predictive Value in Human Cancers / Magali Olivier
Assessing TP53 Status in Human Tumors: Lessons from Breast Cancer / Anita Langerød, Magali Olivier and Anne-Lise Børresen-Dale
TP53 Germline Mutations: Genetics of Li-Fraumeni Syndrome / Doua Bakry and David Malkin
Tp53 Gene Therapy for Cancer Treatment and Prevention / Robert E. Sobol, Yong-Song Guan, Long-Jiang Li, Wei-Wei Zhang and Zhaohui Peng, et al.
Upstream Targets in the p53 Pathway / Anna R. McCarthy and Sonia Lain
p53-Reactivating Molecules as Research Tools and Anticancer Drugs / Vera V. Grinkevich, Andreas Warnecke and Galina Selivanova
Targeting Mutant p53 for Improved Cancer Therapy / Jinfeng Shen, Vladimir J. N. Bykov and Klas G. Wiman
p53 Immunotherapy of Cancer / Hakim Echchannaoui and Matthias Theobald
Designing p53 Trials: A Surgical Oncologists View / Daniela Kandioler, Sonja Kappel and Brigitte Wolf
p53 in the Clinic: A Pathologist's View / Philippe Bertheau, Jean-François Fléjou, Yves Allory, Pascale Varlet and Sylvie Lantuejoul, et al.
Genetic Counseling for TP53 Germline Mutations / Maria Isabel Waddington Achatz and Patricia Ashton-Prolla.