Book[edited by] Robert Terkeltaub.
Summary: Dr. Robert Terkeltaub, presents the state-of-the-art, clinically-focused coverage you need to manage these increasingly prevalent diseases. Diagnose the full range of crystal arthropathies-including pseudogout, intercritical gout, hyperuricemia, and gouty arthritis-and treat your patients effectively with discussions of recently-approved drugs like Uloric and those currently under review, such as Kristexxa and Colcryst. With coverage of the latest therapies, preventions, and imaging studies, this comprehensive resource is ideal for any physician who diagnoses, treats, and manages gout and crystal-induced arthropathies. Stay current on recent developments such as uricosuric therapy and inhibitor therapy; gout flare prophylaxis and colchicines; ultrasound in the diagnosis of crystal deposition diseases; imaging of gout, CPPD, and hydroxyapatitie deposition diseases; and uricase therapy of gout. Manage the full range of crystal arthropathies with 25 clinically-focused chapters on pseudogout, intercritical gout, hyperuricemia, gouty arthritis, and more. Treat your patients effectively using the latest information on drug treatments, from the recently-approved Uloric to Kristexx and Colcryst, which are still under review. The tools to you need to diagnose, treat, and manage gout and other crystal arthropathies.
Contents:
Basic concepts
Articular pathology of gout, calcium pyrophsophate dihydrate and basic calcium phosphate crystal deposition arthropathies
Synovial fluid crystal analysis
Gout
Purine metabolism in the pathogenesis of hyperuricemia and inborn errors of purine metabolism associated with disease
Renal basis of hyperuricemia
Tophus biology and pathogenesis of monosodium urate crystal-induced inflammation
Gout: epidemiology and risk factors
Genetics of gout
Diagnosis of gout
Clinical features of gout
Treatment of acute gout
Diet, alcohol, obesity, hyperuricemia, and risk of gout
Uricosuric therapy of hyperuricemia in gout
Xanthine oxidase inhibitor treatment of hyperuricemia
Uricase therapy of gout
Prophylaxis of attacks of acute gouty arthritis
Overview of gout therapy strategy and targets, and the management of refractory disease
Quality of care in gout
Health-related quality of life and outcome measures in gout
Asymptomatic hyperuricemia: cardiovascular and renal implications
Calcific crystal arthropathies
Pathogenesis and molecular genetics of calcium pyrophasphage dihydrate crystal deposition disease
Calcium pyrophosphate dihydrate crystal deposition: epidemiology, clinical features, diagnosis, and treatment
Basic calcium phosphate crystal arthropathy
Crystalline disorders associated with renal disease including oxalate arthropathy
Imaging of gout and other crystal deposition arthropathies
Plain radiography and advanced imaging of gout
Plain radiography and advanced imaging of calcium pyrophosphate dihydrate crystal deposition disease and of arthropathy associated with basic calcium phosphate crystal deposition
Ultrasound in the diagnosis of crystal deposition disease
Creating a better future of diagnosis and treatment of gout and other crystal arthropathies.