Bookedited by Ronald Cohn, Stephen Scherer, Ada Hamosh.
Summary: First published in 1966, Thompson and Thompson Genetics and Genomics in Medicine has become an essential textbook for medical students, genetic counseling students, students in laboratory medicine, and more advanced trainees. With its focus on fundamental principles in human genetics and genomics and their application to medicine, the book has served many as a well-thumbed resource they return to over and over. Such students can continue to depend on this valuable text, joining those in newer fields of genome data analysis for all they need to know about genetics and genomics throughout their basic science training, clinical placements and beyond. Coverage includes new discoveries--such as the functional roles of non-coding RNAs, chromatin regulation and epigenetics--latest technologies, and new diagnoses they are enabling.
Contents:
Introduction
Introduction to the Human Genome
The Human Genome : Gene Structure and Function
Human Genetic Diversity : Human Genetic Diversity: Genomic Variation
Principles of Clinical Cytogenetics and Genome Analysis
The Chromosomal and Genomic Basis of Disease : Disorders of the Autosomes and Sex Chromosomes
Patterns of Single-Gene Inheritance
Principles of Clinical Epigenetics
Complex Inheritance of Common Multifactorial Disorders
Population Genetics for Genomic Medicine
Identifying the Genetic Basis for Human Disease
The Molecular Basis of Genetic Disease
The Molecular, Biochemical, and Cellular Basis of Genetic Disease
The Treatment of Genetic Disease
Developmental Genetics and Birth Defects
Cancer Genetics and Genomics
Genetic Counseling and Risk Assessment
Preconception and Prenatal Screening and Diagnosis
Application of Genomics to Medicine and Individualized Health Care
Ethical and Social Issues in Genetics and Genomics.