Bookeditors, Robert T. Means, Jr, George M. Rodgers, Bertil Glader, Daniel A. Arber, Frederick R. Appelbaum, Angela Dispenzieri, Todd A. Fehniger, Laura Michaelis, John P. Leonard
Summary: Selected as a Doody's Core Title for 2023! Comprehensive in scope and thoroughly up to date, Wintrobe's Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists"-- Provided by publisher
Contents:
Examination of the blood and bone marrow
Clinical flow cytometry
Cytogenetics
Molecular diagnosis in hematology in hematology
Origin and development of blood cells
The birth, life, and death of red blood cells: erythropoiesis, the mature red blood cell, and cell destruction
Neutrophilic leukocytes
The human eosinophil
Mast cells and basophils: ontogeny, characteristics, and functional diversity
Monocytes, macrophages, and dendritic cells
Lymphocytes and lymphatic organs
B lymphocytes
T lymphocytes
Natural killer and innate lymphoid cells
Major histocompatibility complex
Complement system
Megakaryocytes
Platelet structure
Platelet function in hemostasis and thrombosis
Blood coagulation and fibrinolysis
Endothelium: angiogenesis and the regulation of hemostasis
Red cell, platelet, and white cell antigens
Transfusion medicine
Anemia: general considerations
Iron deficiency and related disorders
Sideroblastic anemias
Hemochromatosis
Porphyrias
Hereditary spherocytosis, hereditary elliptocytosis, and other disorders associated with abnormalities of the erythrocyte membrane
Hereditary hemolytic anemias due to red blood cell enzyme disorders
Autoimmune hemolytic anemia
Paroxysmal nocturnal hemoglobinuria
Acquired nonimmune hemolytic disorders
Sickle cell anemia and other sickling syndromes
Thalassemia syndromes: quantitative disorders of globin chain synthesis
Hemoglobins with altered oxygen affinity, unstable hemoglobins, M-hemoglobins, and dyshemoglobinemias
Megaloblastic anemias: disorders of impaired DNA synthesis
Inherited aplastic anemia syndromes germline
Acquired aplastic anemia
Red cell aplasia: acquired and congenital disorders
Congenital dyserythropoietic anemias
Anemia of inflammation and of systemic disorders
Anemias during pregnancy and the postpartum period
Anemias unique to the fetus and neonate
Erythrocytosis Diagnostic approach to the bleeding disorders
Thrombocytopenia: pathophysiology and classification
Thrombocytopenia caused by immunologic platelet destruction
Thrombotic thrombocytopenic purpura, hemolytic-uremic syndrome, and related disorders
Miscellaneous causes of thrombocytopenia
Bleeding disorders caused by vascular abnormalities
Thrombocytosis and essential thrombocythemia
Qualitative disorders of platelet function
Inherited coagulation disorders
Acquired coagulation disorders
Thrombosis and antithrombotic therapy
Diagnostic approach to tissue examination and testing
Neurtropenia
Qualitative disorders of leukocytes
Lysosomal abnormalities of the monocyte-macrophage system: Gaucher and Niemann-Pick diseases
Langerhans cell histiocytosis
Pathology of langerhans cell histiocytosis and other histiocytic proliferations
Infectious mononucleosis and other Epstein-Barr virus-related disorders
Primary immunodeficiency diseases
Human immunodeficiency virus infection
Disorders of the spleen
Tumors of the spleen
Hematopoietic neoplasms: principles of pathologic diagnosis ; Principles of targeted therapies for hematologic malignancies
Infectious complications in hematologic malignancies
Immunotherapy
Gene therapy for hematopoietic stem cell disorders
Molecular genetics of acute leukemia
Diagnosis and classification of the acute leukemias and myelodysplastic syndromes
Acute lymphoblastic leukemia in adults
Acute myeloid leukemia in adults
Acute lymphoblastic leukemia in children
Acute myeloid leukemia in children
Acute promyelocytic leukemia
Myelodysplastic syndromes
Clonal hematopoiesis of indeterminate potential and myeloid diseases
Pathology of the myeloproliferative neoplasms
Chronic myeloid leukemia
Polycythemia vera
Myelofibrosis
Eosinophilic neoplasms and hypereosinophilic syndrome
Systemic mastocytosis
Diagnosis and classification of lymphomas
Molecular genetic aspects of non-Hodgkin lymphomas
Non-Hodgkin lymphoma in children
Chronic lymphocytic leukemia
Hairy cell leukemia
Cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome
Hodgkin lymphoma in adults
Hodgkin lymphoma in children
Practical approach to the evaluation of monoclonal gammopathies
Molecular genetic aspects of plasma cell disorders
Monoclonal gammopathy of undetermined significane and smoldering multiple myeloma
Mutiple myeloma
Immunoglobulin light chain amyloidosis
Waldenström macroglobulinemia
Monoclonal gammopathies of clinical significance
Hematopoietic cell transplantation
Hematopoietic cell transplantation for nonmalignant disorders
Hematopoietic cell transplantation for hematologic malignancies
Graft-vs-host disease and graft-vs-tumor response
Late effects after hematopoietic cell transplantation