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- ArticleBiglan AW, Brown SI, Cignetti FE, Linn JG.Ann Ophthalmol. 1977 Jun;9(6):799-801.A 46-year-old man with Wegener's granulomatosis developed corneal ulceration and descemetocele. He was treated with a penetrating keratoplasty which has remained clear for 22 months. With the increased life expectancy of this disease corneal rehabilitation is increasingly important and possible.