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- Bookedited by Victor M. Goldberg, Arnold I. Caplan.PrintLocationVersionCall NumberItems
- ArticleWorthington RW, Bertschinger HJ, Mülders MS.J Med Microbiol. 1979 Nov;12(4):497-501.Injection of Clostridium welchii (C. perfringens) type D epsilon toxin into sheep caused large increases in catecholamine and cyclic adenosine 3',5'-monophosphate levels and moderate increases in cyclic guanosine 3',5'-monophosphate levels. Haemoconcentration also occurred. It is suggested that a rapidly developing brain oedema is the stimulus for a release of catecholamines which in turn activates adenyl cyclase. The resulting rise in cAMP causes glycogenolysis and hyperglycaemia.