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- Book[edited by George M. Hall].
- ArticleStarzl TE, Jones AF, Terblanche J, Usui S, Porter KA, Mazzoni G.Lancet. 1979 Jan 20;1(8108):127-30.Extracts from dog livers which had been regenerating for 24, 48, and 72 h after hepatectomy were infused for 6 h into the left portal vein of animals which had fresh portacaval shunts (Eck fistula) and which were killed 2 and 3 days later. The brief exposure to the 48-h and especially the 72-h regenerating liver extracts induced a delayed proliferative response predominantly in the left liver lobes, with a slight spillover effect to the right liver lobes but none to the kidney. The response reached its peak 3 days later. In the left but not the right liver lobes, both the 48-h and the 72-h regenerating liver extract reversed the atrophy ordinarily caused by Eck fistula in 3 days and partly prevented the ultrastructural hepatocyte deterioration characteristic of Eck fistula. The active liver extracts apparently contained a growth-control factor or factors which is (are) not insulin or glucagon.
- BookWith supplementary studies by E. Franklin Frazier and Robert D. Leigh. A report to the Temporary Commission on the Need for a State University.Digital Access Full text via HathiTrust, 1948