Today's Hours: 8:00am - 10:00pm
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Journal
    Summary: Includes descriptions of physical and physiochemical analytical methods and assays, containers, reagents, standard and buffer solutions plus dosage forms and biological tests.
    Print Access
    Location
    Version
    Call Number
    Items
    Reference (Shelved at Information Desk)
    <1997>
    RS141.28 .E95
    2
    Retired Reference (Downstairs)
    v. 1-5, 1980
    RS141.28 .E95
    8
    Request
  • Article
    Laguens RP, Colmerauer ME, Segal A, Pasqualini CD.
    Int J Cancer. 1978 Jun 15;21(6):779-83.
    In an experimental model conditioning for enhancement, an AKR lymphoma was made to grow in BALB/c mice, permitting the simultaneous comparison of tumor-bearing (progressor) and tumor-rejecting (regressor) animals. By immunofluorescence using as target AKR lymphoma and normal thymus cells, both acetone-fixed and unfixed, it was observed that the allogeneic progressor serum contained three antibodies, two of which could be asborbed by thymocytes while the other combined selectively with the acetone-fixed lymphoma target. This tumor-specific antibody could not be detected in regressor serum which, on the other hand, could be completely absorbed by thymocytes. The identification of this acetone-resistant tumor antigen led to the preparation of aceton-treated acellular lymphoma extracts: a precipitate was obtained which upon inoculation in BALB/c mice produced an antiserum that combined selectively with lymphoma targets. In vivo experiments showed that pretreatment with this antigen led to a significant increase in allogeneic tumor incidence, 76% as compared to 37% in the controls. It is concluded that in this allogeneic model, an acetone-resistant tumor-specific antigen and the corresponding antibody are involved in tumor enhancement.
    Digital Access Access Options