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  Jornada médica

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  v. [3-4, 6-7], 8-9, [10], 11-16, [17], [1949-50, 1952-54], 1955-57, 1958.

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• Article

  Release of motilin after duodenal acidification.

  Mitznegg P, Bloom SR, Domschke W, Domschke S, Wunsch E, Demling L.

  Lancet. 1976 Apr 24;1(7965):888-9.

  The physiological stimulus leading to motilin release in man has not yet been determined. Six healthy volunteers had 3-minute intraduodenal infusions of acid, alkali, or saline solutions. After infusing acid, plasma-motilin rose by 90% at 4 min and was still significantly raised at 45 min, whereas there was an insignificant fall in plasma-motilin after alkali and no change after saline solution. Release of motilin after duodenal acidification may be an important factor in inhibiting gastric emptying.

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