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- ArticleGrant HR.J Laryngol Otol. 1976 May;90(5):433-40.This paper describes a multiagent protocol of chemotherapy suitable for head and neck cancer which has been used at King's College Hospital since 1974. It studies a twelve month period in which 30 patients received chemotherapy and offers details of eight patients who were free of tumour from two to twelve months after completing the treatment. No statistical evaluation is attempted as the follow-up period is so short and the clinical material so diverse.