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  • Book
    editor, Johannes Häberle.
    Contents:
    Foreword : current approach to hyperammonemia / Johannes Häberle
    Ammonia metabolism in humans : production and removal / Daniel Rabier
    Neurobiology of ammonia / Vicente Felipo
    Ammonia toxicity to the brain / Olivier Braissant
    Oxidative and nitrosative stress in ammonia neurotoxicity / Marta Skowroñska & Jan Albrecht
    Preanalytical and analytical aspects of ammonia determination / Camilla Scott & Simon Olpin
    Inherited disorders leading to hyperammonemia in children / Arunabha Ghosh & Andrew Morris
    Inherited disorders leading to hyperammonemia in adults / Valerie Walker
    Role of cerebral ammonia toxicity in hepatic encephalopathy / Natalia Qvartskhava, Markus S. Jördens, Boris Görg & Dieter Häussinger
    Role of brain imaging for demonstrating ammonia-induced changes / Ileana Pacheco-Colón, Stanley Fricke & Andrea Gropman
    Medical treatment of hyperammonemia / Marie-Cécile Nassogne & Marie-Françoise Vincent
    Extracorporeal detoxifcation as a treatment of acute hyperammonemia / Nicholas Ah Mew & Marshall Summar
    Organ and cell-based replacement therapy for the treatment of urea cycle disorders / Shirou Matsumoto & Fumio Endo
    New treatment options for hyperammonemia / George A. Diaz.
    Digital Access Future Med 2014
  • Article
    Gassel WD.
    Klin Wochenschr. 1978 Oct 15;56(20):991-9.
    In modifying the agar culture technique of mouse bone marrow cells Robinson et al. in 1970 described the in vitro culture of the human colony-forming cell. Since that time a number of data accumulated which markedly improved our knowledge of the regulation of normal and pathological hematopoiesis. A summary of the up-to date results is presented focusing mainly on disturbances of the colony-forming cells in peripheral blood and bone marrow of patients with hematological disorders. Furthermore, the findings on human urinary CSF excretion which exerts an action on mouse bone marrow are discribed. The somewhat contradictory results obtained with different methods are discussed in the light of the actual hypotheses.
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