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  • Book
    Brett Duane, editor.
    Summary: This book provides the why, what and how on delivering a sustainable dental practice. Dentists have a professional duty to support optimal oral health. They also have a moral duty to do so in a way that leaves the smallest footprint on this planet and takes their impacts on the environment and society into account. This book helps the reader to develop a sustainable practice, driven by prevention and delivering the right care at the right time and at the right place, within systems of universal, needs-based access to care. Readers learn how to opt for a practice that is supplied with sustainable energy and encourages biodiversity while building models of care that maximize remote patient engagement and avoid travel. Clear guidance is given on responsible decontamination, waste management and environmentally sensitive ways of managing people with anxiety or behavioural difficulties within the dental setting. The future of dentistry products and innovations to reduce environmental impacts in the dental practice are discussed. This book is a must-have for dentists, dental students and all members of the dental team.

    Contents:
    Sustainable Dentistry - An Urgent Need for Change
    Building a sustainable dental practice (considering the need to rebuild, material, location)
    Habitat level considerations for build options
    Reducing the energy needs of your dental practice
    Prevention; The sustainable practice initiative
    A guide to how to reduce the impact of PPE in your dental practice 200
    Responsible decontamination
    Supporting people and their behaviour in the dental setting as sustainably as reasonably achievable
    Buying sustainably and ethically for the dental practice
    Responsible waste management; using resources efficiently/responsibly
    The Future of dentistry products; How can we redesign the products we create
    Sustainability: The need to transform oral health systems
    Conclusion.
    Digital Access Springer 2022
  • Article
    McClure WR, Cech CL.
    J Biol Chem. 1978 Dec 25;253(24):8949-56.
    The mechanism of rifampicin inhibition of Escherichia coli RNA polymerase was studied with a newly developed steady state assay for RNA chain initiation and by analysis of the products formed with several 5'-terminal nucleotides. The major effect of rifampicin was found to be a total block of the translocation step that would ordinarily follow formation of the first phosphodiester bond. These effects were incorporated into a steric model for rifampicin inhibition. Additional minor effects of the enzyme bound inhibitor were to increase slightly the lifetime of RNA polymerase on the lambdaPR' promoter and to increase by two the apparent Michaelis constants of the initiating triphosphates. The products formed by RNA polymerase in the presence of rifampicin belong nearly exclusively to the class pppPupN. No evidence for the accumulation of such molecules was obtained in vivo.
    Digital Access Access Options