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- Journaleditor-in-chief, Karl C. Golnik, MD.Summary: NANOS NOTE (Neuro-Ophthalmology Techniques of Examination) for NON-neuro-ophthalmologists, produced by NANOS (The North American Neuro-ophthalmology Society), is designed to teach and improve implementation of basic neuro-ophthalmic examination techniques and increase confidence in practitioners who use these skills to evaluate patients with visual and neurological complaints.Digital Access STAT!Ref Current yearLimited to 2 simultaneous users
- ArticleNesmeianova MA, Maraeva OB, Kolot MN, Kulaev IS.Biokhimiia. 1978 Oct;43(10):1783-9.The effect of exogenous orthophosphate and mutations in regulatory genes of alkaline phosphatase on the level of nonspecific acid phosphatase was studied. The level of this enzyme as well as the level of alkaline phosphatase were shown to be regulated by exogenous orthophosphate being derepressed under phosphate starvation. The derepression of acid phosphatase is accompanied by more rapid secretion of enzyme from membranes to soluble fraction. Mutations in all the four regulatory genes decrease the level of enzyme in cells. Genes phoR and phoS, participating in regulation of alkaline phosphatase, are required for the derepression of acid phosphatase under the conditions of phosphate starvation.