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- BookEdward Kim, Upendra Parvathaneni, Meng Xu Welliver, editors.Summary: This practical guide to the use of radiotherapy for the treatment of sarcomas and skin cancers covers a wide range of disease scenarios, identifying which treatment techniques are applicable in particular clinical circumstances. Among the conditions considered are extremity soft tissue sarcomas, retroperitoneal soft tissue sarcomas, bone sarcomas, uterine sarcomas, chordomas, pediatric sarcomas, squamous cell carcinomas, basal cell carcinomas, melanomas, Merkel cell carcinomas, and cutaneous lymphomas. Detailed attention is devoted to the issues and considerations of relevance in everyday practice when treating these diseases. The use of multiple radiotherapy techniques and procedures, including IMRT, brachytherapy, radiosurgery, and particle therapy, is fully explained, and the role of radiotherapy in combination with chemotherapy and emerging therapeutics such as immunotherapy and biologic anticancer agents is also addressed. The book will be of high value for practicing radiation oncologists, medical and surgical oncologists, medical physicists, medical dosimetrists, trainees, and other medical professionals.
Contents:
PART I Sarcomas: Extremity soft tissue sarcoma
Retroperitoneal soft tissue sarcoma
Gynecologic sarcomas
Bone sarcomas
Chordomas
Oligometastatic sarcomas
Pediatric sarcomas
Particle therapy for sarcomas
Chemotherapy / radiosensitizers
PART II Other soft tissue tumors: Desmoid fibromatosis
Hemangiopericytomas / solitary fibrous tumors
Angiosarcomas
Dermatofibrosarcoma protuberans
PART III Skin cancers: Squamous cell carcinomas
Basal cell carcinomas
Melanomas
Merkel cell carcinomas
Cutaneous lymphomas. - ArticleGravem A, Engstrand E, Guleng RJ.Acta Psychiatr Scand. 1978 Nov;58(5):384-8.The clinical effect of cis(Z)-clopenthixol has been compared with that of clopenthixol, which is a mixture of the pharmacologically active cis(Z)-isomer and the inactive trans(E)-isomer. In the 2-month double-blind trial were included 57 psychotic patients, mainly schizophrenics. Ratings evaluating severity of illness, therapeutic effect, possible interference of side effects with the patient's functioning, as well as any individual side effects were done at months 0, 1, and 2. The antipsychotic effect of cis(Z)-clopenthixol was found equal to that of clopenthixol whereas the cis(Z)-isomer on a mg/mg basis was twice as active as clopenthixol. Apart from the finding that the unspecific sedative effect appeared to be less marked with cis(Z)-clopenthixol, the type, degree, and frequency of side effects were the same in the two groups of patients. More than half of the patients experienced no side effects.