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  • Book
    Pradeep Vaideeswar, editor.
    Summary: The book covers 75 autopsy-based cases (about 75) of common and uncommon presentations of various cardiovascular diseases (CVDs). It emphasizes the importance of the autopsies, which have played a pivotal role in the understanding of the pathology and hence the clinical manifestations of several CVDs. The book attempts to present the material from the perspective of the autopsy table. It uses the clinical data as the initial framework and the autopsy findings to develop a true understanding of the disease and the associated pathophysiology of the condition with final clinico-pathological correlation. Each case covers a complete journey of the deceased patient concisely under the following headingstitle, clinical history, autopsy findings and discussion, which includes a brief review of the literature. The text is accompanied by relevant high-quality macroscopic and microscopic images. The book is relevant for specialists in pathology, cardiology, cardiac surgery, internal medicine, critical care and pediatrics.

    Contents:
    Utility of Autopsy with Special Reference to Cardiovascular Diseases
    Basic Cardiac Anatomy and Dissection
    Autopsy-based Clinicopathological Cases of Pericardial Diseases
    Autopsy-based Clinicopathological Cases of Post-inflammatory Valvular Anomalies
    Autopsy-based Clinicopathological Cases of Infective/Inflammatory Valvular Anomalies
    Autopsy-based Clinicopathological Cases of Non-inflammatory Valvular Anomalies
    Autopsy-based Clinicopathological Cases of Ischemic Myocardial Disorders
    Autopsy-based Clinicopathological Cases of Non-ischemic Myocardial Disorders
    Autopsy-based Clinicopathological Cases of Cardiac Tumors (Primary / Secondary)
    Autopsy-based Clinicopathological Cases of Systemic Vascular Pathology
    Autopsy-based Clinicopathological Cases of Pulmonary Vascular Pathology. .
    Digital Access Springer 2022
  • Journal
    Print 1960-
  • Article
    Orstavik TB, Glenner GG.
    Acta Physiol Scand. 1978 Aug;103(4):384-93.
    Kallikrein was located by the direct immunofluorescence technique to the granule-containing luminal portion of pancreatic acinar cells. For the demonstration of the intracellular distribution of pancreas kallikrein, in vivo fixation of the gland was necessary. No kallikrein was found in the duct cells or in the islets of Langerhans. Quantitation by single radial immunodiffusion showed that the concentration of kallikrein in the presence was 1.32 +/- 51 microgram/g wet weight, i.e. 1/91 that of the rat submandibular gland. Bz-Arg-OEt-esterases were in the pancreas found as pro-enzyme but as active enzyme in the submandibular gland. Trypsin-like esterases, hydrolyzing epsilon-amino caproic acid naphtol-AS-D.HBr (ACA), were found in the active form in both submandibular gland and pancreatic homogenates. The submandibular gland contained per g wet weight 6 times as much ACA-esterase activity as the pancreas. In the submandibular gland, kallikrein and ACA-esterase activity were found together in practically all granular tubular cells. Thus, the granular tubular cell contains kallikrein as well as other trypsin-like enzymes like the ACA-esterase, and is in this way comparable to the pancreatic acinar cell. An extraglandular function of kallikrein is suggested for the pancreas in contrast to other kallikrein-containing exocrine organs.
    Digital Access Access Options