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- BookSujata Das, editor.Summary: The book covers various aspects of the management of keratoconus, which is a leading cause of visual impairment in young adults. It focuses on the epidemiology and risk factors of keratoconus with a special focus on Southeast Asia. Keratoconus affects the quality of vision, thereby affecting the quality of life. While most patients present with defective vision, many are diagnosed accidentally during screening for refractive surgery. The book covers the varied epidemiology of keratoconus across different parts of the world. It discusses many systemic and ocular diseases associated with keratoconus. The book covers the newer diagnostic techniques and various treatment procedures for keratoconus, helping in diagnosing keratoconus in the early stages and closely watching the progression. It discusses various contact lenses to improve vision quality; widely used collagen crosslinking, and its various modifications for halting the progression. It also explains the surgical approach for keratoconus, such as penetrating keratoplasty, lamellar keratoplasty and other lens-assisted procedures. The book is relevant for general ophthalmologists and cornea specialists.
Contents:
Epidemiology of Keratoconus
Etiology and Risk Factors of Keratoconus
Biomechanics of Keratoconus
Pathophysiology and Histopathology of Keratoconus
Clinical Diagnosis of Keratoconus
Classifications and Patterns of Keratoconus
Differential Diagnosis of Keratoconus
Keratoconus in Children
Allergic Eye Disease and Keratoconus
Topography and Tomography of Keratoconus
Newer Diagnostic Technology for Diagnosis of Keratoconus
Acute Corneal Hydrops: Etiology, Risk Factors, and Management
Contact Lenses for Keratoconus
Corneal Cross-Linking in Keratoconus
Penetrating Keratoplasty in Keratoconus
Lamellar Keratoplasty in Keratoconus
Intracorneal Ring Segments in Keratoconus
Intraocular Lens (IOL) Implantation in Kertaoconus
Stromal Augmentation Techniques for Keratoconus
Cataract Surgery in Keratoconus
Refractive Surgery in Management of Keratoconus
Artificial Intelligence in the Diagnosis and Management of Keratoconus
Changing Paradigm in the Diagnosis and Management of Keratoconus. - ArticleNorlén L, Sundin T.Acta Pharmacol Toxicol (Copenh). 1978;43 Suppl 2:31-4.The effect of alpha-adrenolytic treatment (phenoxybenzamine) was studied in 8 patients with lower motor neuron lesions (autonomous bladders). In the cystometrograms, the bladders were more hypotonic and the "autononous waves" appeared at a higher level of filling or were totally extinguished after this pharmacological treatment. With an isotonic volume registration method, a bladder volume increase was recorded after alpha-adrenergic blockage. Using spincterometry or urethral pressure profile studies, a decrease in the urethral resistance was observed after alpha-adrenolytic treatment, resulting in a decrease in residual urine. This decrease in bladder wall tension and in residual urine effected an increased functional bladder capacity in patients with autonomous bladders.