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- BookMalte Renz, Elisabeth J. Diver, Whitfield B. Growdon, Oliver Dorigo.Summary: "This revised and updated new edition of a best-selling text remains a fast and convenient overview of the clinical trials in gynecologic cancer treatment, outlining the evidence base of treatment decisions in uterine, ovarian, cervical, and vulvar cancers, and gestational trophoblastic neoplasia. Residents and fellows will find this book an indispensable reference, while practitioners will welcome it as a clarification of the evidence base for treatment options. *Gives a convenient summary of trials in Gynecologic Oncology *Supplies an invaluable revision primer for those undertaking certification *Provides a uniquely up-to-date resource"-- Provided by publisher.
Contents:
Uterine Malignancies
Ovarian Malignancies
Cervical Cancer
Vulvar Cancer
Gestational Trophoblastic Neoplasia (GTN). - Articlevan Alphen GW, Dutilh CE, de Deckere EA.Prostaglandins Med. 1978 Aug;1(2):151-7.Iris, and to a lesser extent ciliary body, from cat and rabbit produce considerable amounts of prostacyclin (PGI2) after incubation of the tissue with 1-14C arachidonic acid. These tissues also generate PGI2-like material after gentle squeezing. It is likely that major metabolites found previously in iris and aqueous humor actually were 6-keto-PGF1alpha. It is concluded that PGH2 and PGI2 are synthetized at the same location. PGI2 induces a contraction of the sphincter and dilator and a relaxation of the ciliary muscle if the tissues had been previously exposed to indomethacin. Thromboxane A2 (TxA2) has either no effect or may cause a slight relaxation of the sphincter.