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  • Book
    edited by Grant E. Garrigues, Marc J. Richard and Mark J. Gage.
    Summary: From the sternoclavicular joint to the distal phalanx, Skeletal Trauma of the Upper Extremity is a practical, one-volume resource covering all aspects of upper limb trauma and surgery. Comprehensive in scope, it features a multidisciplinary, step-by-step approach to evaluation and management, including concise background information and a detailed focus on practical points and surgical techniques. Written by global experts in traumatology, sports medicine, shoulder, elbow, and hand surgery, this richly illustrated guide brings you into the operating room with leaders in the field. Offers detailed, practical guidance from the originators and/or masters of each procedure, along with multiple, illustrated surgical technique descriptions. Includes pearls and pitfalls, preoperative evaluation and indications, surgical techniques, rehabilitation, and management of complications. Features tables and figures throughout that clearly demonstrate surgical tips and tricks. Identifies controversial topics and covers current challenges such as arthroscopic coracoclavicular/acromioclavicular joint reconstruction, reverse total shoulder arthroplasty for proximal humerus fracture, total elbow arthroplasty for fracture, interosseous membrane reconstruction of the forearm, and many more. Contains more than 500 high-quality illustrations, including anatomical and surgical illustrations, surgical photographs, ultrasounds, and x-rays. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
    Digital Access
    Provider
    Version
    ScienceDirect
    2022
    ClinicalKey
    2022
  • Article
    Thust R, Warzok R, Grund E, Mendel J.
    Mutat Res. 1978 Sep;51(3):397-402.
    Samples of two human livers taken during operation of kidney donor patients were processed for microsome fractions and used for metabolization of cyclophosphamide (CP) and dimethylnitrosamine (DMN) in combination with the NADPH-generating system. Rat-liver microsomes were checked for comparison. Induction of chromatid aberrations and sister-chromatid exchanges in a newly isolated clone of Chinese hamster fibroblasts served as indicators of activity. Human S-9 fractions standardized on protein content showed strong variations of CP and DMN activation. Whereas liver microsomes of one patient (who also suffered from Gaucher's disease) were highly active for both pre-carcinogens and metabolized DMN at the same level as the uninduced rat-liver microsomes, the S-9 fraction from the second patient failed to activate CP, but was distinctly positive for DMN. It is suggested that samples of liver and other organs of renal transplant donors might be a practicable source of freshly prepared human microsome fractions usable in biochemical, genetic and carcinogenetic studies. Problems concerning the extrapolation of results are discussed.
    Digital Access Access Options