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  • Book
    Jenni Punt, Sharon A. Stranford, Patricia P. Jones, Judy A. Owen.
    Summary: The 8th edition of 'Kuby Immunology' presents an up-to-date and comprehensive introduction to the principles and findings of immunology. It contains full-colour illustrations, study questions, study aids and much more.

    Contents:
    I. Introduction, p.1
    Chapter 1: Overview of the Immune System, p.1
    Chapter 2: Cells, Organs and Microenvironments of the Immune System, p.31
    Chapter 3: Recognition and Response, p.69
    II. Innate Immunity
    Chapter 4: Innate Immunity, p.113
    Chapter 5: The Complement System, p.165
    III. Adaptive Immunity: Antigen Receptors and MHC
    Chapter 6: The Organization and Expression of Lymphocyte Receptor Genes, p.205
    Chapter 7: The Major Histocompatibility Complex and Antigen Presentation, p.249
    IV. Adaptive Immunity: Development
    Chapter 8: T-Cell Development, p.293
    Chapter 9: B-Cell Development, p.321
    V. Adaptive Immunity: Efeector Responses
    Chapter 10: T-Cell Activation, Helper Subset Differentiation, and Memory, p.353
    Chapter 11: B-Cell Activation, Differentiation, and Memory Generation, p.391
    Chapter 12: Effector Responses: Antibody- and Cell-Mediated Immunity, p.433
    Chapter 13: Barrier Immunity: The Immunology of Mucosa and Skin, p.473
    Chapter 14: The Adaptive Immune Response in Space and Time, p.511
    V. Adaptive Immunity: Efeector Responses
    Chapter 15: Allergy, Hypersensitivities, and Chronic Inflammation, p.549
    Chapter 16: Tolerance, Autoimmunity, and Transplantation, p.593
    Chapter 17: Infectious Diseases and Vaccines, p.637
    Chapter 18: Immunodeficiency Diseases, p.681
    Experimental Systems Methods
    Chapter 19: Cancer and the Immune System, p.727
    VII. Experimental Systems Methods
    Experimental Systems and Methods, p.759
    Digital Access ProQuest Ebook Central [2018]
    Limited to 1 simultaneous users
  • Article
    Lowenthal DT, Onesti G, Mutterperl R, Affrime M, Martinez EW, Kim KE, Busby P, Shirk J, Swartz C.
    J Clin Pharmacol. 1978 Oct;18(10):500-8.
    Minoxidil was used to treat 26 patients (17 to 67 years old) with severe hypertension and varying degrees of renal function. Our object was to assess long-term clinical efficacy, kinetics (acute and chronic), and bioavailability of minoxidil in chronic renal insufficiency. Minoxidil, 27 to 30 mg per day, decreased systolic and diastolic blood pressure during the first three months of therapy. Between the third and 24th months (30 months in one patient) there was no further change. Propranolol or clonidine was needed to control heart rate, and furosemide or dialysis was needed to control edema induced by minoxidil. Renal function improved in some of the mildy azotemic patients. Minoxidil kinetics after the customary dose did not differ whether the drug was taken as tablet or solution. Kinetic parameters during chronic administration of minoxidil did not differ from those after acute administration. The kinetics in chronic renal insufficiency do not differ from these in subjects with normal renal function.
    Digital Access Access Options