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- Bookeditors, Wilmar M. Wiersinga, George J. Kahaly.Contents:
Diagnosis and pathogenesis
Clinical manifestations
Orbit-thyroid relationship
Epidemiology
Pathogenesis
Orbital imaging
Diagnosis and differential diagnosis of graves' orbitopathy
Natural history
Management
General management plan for graves' orbitopathy
Combined thyroid-eye clinics
Thyroid treatment
Management of mild graves' orbitopathy
Management of moderately severe graves' orbitopathy
Novel immunomodulatory treatment modalities
Management of very severe graves' orbitopathy: dysthyroid optic neuropathy and corneal breakdown
Local treatment modalities
Rehabilitative surgery
Orbital decompression
Eye muscle surgery
Eyelid surgery
Miscellaneous issues
Quality of life
Socioeconomic impact
The patient's view
Atypical manifestations
Childhood graves' orbitopathy
Comorbidity in graves' orbitopathy
Prevention
Protocols of non-surgical therapies
The amsterdam declaration on graves' orbitopathy
Historical notes on graves' disease.Digital Access Karger 2017 - ArticleGudkov AT, Behlke J.Eur J Biochem. 1978 Oct;90(2):309-12.Ultracentrifuge studies of intact protein L7/L12, of its fragments 27--120, 1--74 and 74--120 and of protein L7/L12 with oxidized methionine residues, indicate that the N-terminal sequence of the protein L7/L12 is responsible for its dimerization. The symmetry model of the dimer is discussed.