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  • Book
    Bruce Alberts, Rebecca Heald, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter ; with problems by John Wilson, Tim Hunt.
    Contents:
    Part I. Introduction to the Cell
    Chapter 1. Cells, genomes, and the diversity of life
    Chapter 2. Cell chemistry and bioenergetics
    Chapter 3. Proteins
    Part II. Basic Genetic Mechanisms
    Chapter 4. DNA, chromosomes, and genomes
    Chapter 5. DNA replication, repair, and recombination
    Chapter 6. How cells read the genome : From DNA to protein
    Chapter 7. Control of gene expression
    Part III. Ways of Working with Cells
    Chapter 8. Analyzing cells, molecules, and systems
    Chapter 9. Visualizing cells and their molecules
    Part IV. Internal Organization of the Cell
    Chapter 10. Membrane structure
    Chapter 11. Small-molecule transport and electrical properties of membranes
    Chapter 12. Intracellular organization and protein sorting
    Chapter 13. Intracellular membrane traffic
    Chapter 14. Energy conversion and metabolic compartmentation : Mitochondria and chloroplasts
    Chapter 15. Cell signaling
    Chapter 16. The cytoskeleton
    Chapter 17. The cell cycle
    Chapter 18. Cell death
    Part V. Cells in Their Social Context
    Chapter 19. Cell junctions and the extracellular matrix
    Chapter 20. Cancer
    Chapter 21. Development of multicellular organisms
    Chapter 22. Stem cells in tissue homeostasis and regeneration
    Chapter 23. Pathogens and infection
    Chapter 24. The innate and adaptive immune systems
    Glossary
    Index.
    Print
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    Call Number
    Items
    Course Reserves: Request at Lane Information Desk
    [2022]
    QH581.2 .M64 2022
    1
  • Article
    Fletcher JR, Ramwell PW.
    Br J Pharmacol. 1978 Oct;64(2):185-91.
    1 Dogs treated with lidocaine (1 mg kg-1 h-1) or indomethacin (1.5 mg/kg) before and after an LD60 dose (1 mg/kg) of E. coli endotoxin survived for at least 72 h. 2 Although all dogs in both treated groups survived, only those treated with indomethacin were significantly protected against the fall in the arterial blood pressure 1 to 2 min following endotoxin administration. 3 Endotoxin increased the plasma prostaglandin F2alpha (PGF2alpha) concentration in the control and lidocaine-treated groups, however, no increase was observed with indomethacin treatment. 4 Neither lidocaine nor indomethacin alone had any significant effect on the parameters measured in this model. 5 Following the administration of endotoxin, lidocaine-treated animals had significantly decreased plasma fibrinogen concentrations when compared to the other groups. 6 This study suggests that lidocaine, a local anaesthetic and a drug widely used for cardiac arrhythmias, might offer protection in endotoxin shock.
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