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- BookPaul D. Sponseller.Contents:
Anatomy and normal development in children / Paul D. Sponseller
Disorders of growth and development in the extremities / Paul D. Sponseller
Disorders of spinal growth and development / Paul D. Sponseller
Miscellaneous disorders of growth and development / Paul D. Sponseller
Skeletal syndromes and systemic disorders in pediatric orthopaedics / Paul D. Sponseller
Neuromuscular disorders in pediatric orthopaedics
Paul D. Sponseller
Pediatric trauma / Paul D. Sponseller and Matthew J. Hadad
Normal values and medications / Paul D. Sponseller and Matthew J. Hadad
Common procedures in pediatric orthopaedics / Paul D. Sponseller.Digital Access Thieme-Connect 2020 - ArticleTiengo A, Fedele D, Muggeo M, Nosadini R, Molinari M, Garotti MC, Crepaldi G.Acta Diabetol Lat. 1978 May-Aug;15(3-4):143-51.Insulin and glucagon have been studied in 20 subjects (both of the subjects' parents were diabetic or in case of only one diabetic parent, the other showed a first degree familiarity of diabetes): 10 showed normal glucose tolerance ('true prediabetics') and 10 impaired glucose tolerance ('genetic chemical diabetes'). Mean insulin response to oral (100 g) and i.v. glucose load (200 mg/kg followed by 20 mg/kg/min for 60 min) and to arginine infusion (25 g in 30 min) was normal in the prediabetics and delayed and higher in the subjects with chemical diabetes as compared to the control group. Glucagon response to arginine was higher, but not significantly, in prediabetics and in subjects with chemical diabetes. In both of these groups glucagon suppression by glucose was not observed. The insulin/glucagon molar ratio was significantly reduced after glucose infusion in these two groups. No correlation was found between insulin and glucagon secretion after arginine or glucose. A possible alteration in the mechanism controlling glucagon secretion even in the earliest phases of diabetes is suggested.