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  • Book
    Poonam Khetrapal Singh, editor.
    Summary: This book discusses the historical context, country experience, and best practices that led to eliminating infectious diseases from the WHOs South-East Asia Region, such as malaria, lymphatic filariasis, yaws, trachoma, and mother-to-child HIV in the mid-twentieth and twenty-first century. The UN Sustainable Development Goals (3.3) targets to end AIDS, tuberculosis, malaria, and neglected tropical diseases and combat hepatitis, water-borne diseases and other communicable diseases by 2030. In this context, this book is of high significance to countries from the SEA region and around the globe. It helps create national strategies and action plans on infectious disease elimination and thus attaining SDG 3.3.

    Contents:
    Introduction: A historic paradigm shift in communicable diseases in South-East Asia: from control to elimination
    Thailand: Elimination of mother-to-child HIV transmission
    Yaws: freeing young children in India from an old scourge
    Maldives: a long battle to banish malaria
    Unburdening the poor: elimination of lymphatic filariasis in Maldives
    Sri Lanka: long battle to eliminate malaria
    Lymphatic filariasis elimination in Sri Lanka: overcoming the odds
    Elimination of lymphatic filariasis in Thailand: a model for best practices
    Trachoma elimination in Nepal: bringing light, preventing darkness
    South-East Asia Region marches ahead on elimination of mother-to-child transmission of HIV and syphilis: Sri Lanka becomes the third country in the SE Asia Region to be validated
    Leveraging health system gains towards eliminating mother-to-child transmission (EMTCT) of HIV and syphilis: How Maldives became the second country in WHO South-East Asia Region to achieve this feat
    Leprosy: accelerating towards a leprosy-free world.
    Digital Access Springer 2021
  • Article
    Davies C, Rickard MD, Bout DT, Smyth JD.
    Parasitology. 1978 Oct;77(2):143-52.
    The unlabelled antibody method was used in the ultrastructural localization of two hydatid fluid antigens, antigen 5 and antigen B, in brood capsules and protoscoleces of Echinococcus granulosus and E. multilocularis. Antigen 5 was found in the parenchyma cells of the protoscolex and brood capsule wall and to a lesser extent in the walls of the flame cells and collecting ducts of the excretory system and in the surrounding interstitial material. It is suggested that, while some excretion of this antigen may occur from the protoscolex, it could also be liberated into the cystic cavity by degeneration of protoscoleces and parenchymal cells of the brood capsule wall. Antigen B was found mainly in the distal cytoplasm and perinuclear cytoplasm of the tegument anterior to the suckers. It is apparently secreted to the outside and was present in the brood capsule contents; it adheres to the anterior surface and the posterior periodic acid-Schiff (PAS)-positive glycocalyx of the protoscolex and to the inner surface of the brood capsule wall. The protoscolex tegument posterior to the suckers was negative. The parenchyma cells of the protoscolex and brood capsule wall were also positive although the intensity of the reaction product was variable.
    Digital Access Access Options