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  • Book
    [edited by] Michael Sabel ; with contributions by Marcel Alexander Kamp, Marion Rapp, Silvio Sarubbo, Maria Smuga.
    Summary: The surgical treatment of infiltrating brain tumors is an extremely challenging and often highly rewarding facet of neurosurgery. The decision-making process involves deeply human interconnections with patients and relatives, cutting-edge neuroscience, and fascinating technology. Video Atlas of Neurophysiological Monitoring in Surgery of Infiltrating Brain Tumors by renowned oncological neurosurgeon Michael Sabel and esteemed contributors demonstrates the practical applications of neurophysiological monitoring to achieve safe removal of infiltrating brain tumors in asleep and awake settings.Organized in three primary parts, the book starts with an introduction including a discussion of the impact and challenges posed by infiltrating gliomas and cerebral metastases and the philosophy behind supramarginal resection. The second part covers critical theoretical components including relevant anatomy, nervous system electricity and fields, transcranial monitoring methods and principles, and direct cortical and subcortical mapping including awake brain surgery. The final part provides insightful, practical guidance on decision making, monitoring set-up, planning of surgical cases, and a summary of accompanying videos- Provided by publisher.

    Contents:
    The Scope of This Book
    The Challenge to Treat Infiltrating Brain Tumors
    The Impact of Lesionectomy on the Prognosis of Infiltrating Intracerebral Tumors
    The Philosophy Behind Supramarginal Resection : Functionality Becomes the Limit
    The Relevant Anatomy of the Functional Systems
    What You Need to Know About Electricity
    Transcranial Monitoring : Methods to Monitor CNS Functions :Principles
    Direct Cortical and Subcortical Mapping
    Checklist for Awake Procedure
    Introduction to the Practical Part
    Setting up the Monitoring
    The Surgery
    Summary: Key Features from the Video
    Epilogue.
    Digital Access
    Provider
    Version
    Thieme-Connect
    2022
    Thieme MedOne Neurosurgery
    2022
  • Article
    Yochem J, Uchida H, Sunshine M, Saito H, Georgopoulos CP, Feiss M.
    Mol Gen Genet. 1978 Aug 04;164(1):9-14.
    We show that a collection of 93 E. coli mutations which map between thr and leu and which block phage lambda DNA replication define two closely linked cistrons. Work published in the accompanying paper shows that these mutations also affect host DNA replication, so we designate them dnaJ and dnaK; the gene order is thr--dnaK--dnaJ--leu. Demonstration of two cistrons was possible with the isolation of lambda transducing phages carrying one or the other or both of the dna genes. These phages were employed in phage vs bacterial complementation studies which unambiguously show that dnaK and dnaJ are different cistrons.
    Digital Access Access Options