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  • Book
    Alfred Abuhamad, Rabih Chaoui.
    Summary: "Covering every aspect of fetal heart examination and all major cardiac malformations, A Practical Guide to Fetal Echocardiography is widely acknowledged as the definitive text in this challenging field. This award-winning title clearly depicts examples of commonly seen abnormalities and day-to-day cases, as well as rare pathology. Authored by renowned experts, the fully updated fourth edition is a lavishly illustrated, easy-to-read text designed to serve as a comprehensive reference for all practitioners involved in cardiac imaging. Features significant revisions including several new chapters, new artwork, and updated reference lists. Discusses disorders in terms of the ultrasound findings with key points summarized at the end of each chapter. Images are accompanied by clear, colorful schematic drawings that depict cardiac abnormalities. Features the addition of Approach to Diagnosis, an algorithm at the end of each chapter to assist providers in reaching the proper diagnosis.^Includes numerous tables that outline common and differentiating features of various cardiac malformations. Covers the technical aspects of the cardiac exam in the first half of the text; the second half features detailed discussions of fetal cardiac malformations, each presented in a practical, methodical format that includes the definition, spectrum of disease and incidence, the use of gray scale, color Doppler, 3D and early gestation ultrasound in diagnosis, followed by the differential diagnosis, prognosis, and outcome. Features a practical, concise, easy-to-use format, making it indispensable for both physicians and sonographers in the detection of congenital heart disease. Winner of British Medical Association Awards 2016: BMA Medical Book of the Year and Obstetrics and Gynecology - First Prize. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone.^Easily convert to audiobook, powering your content with natural language text-to-speech. "-- Provided by publisher.
    Digital Access Ovid 2022
  • Article
    Doss M.
    Leber Magen Darm. 1978 Oct;8(5):278-85.
    Alcohol is a agenrphyrinogenic agent which may cause disturbances in porphyrin metabolism in healthy persons as well as biochemical and clinical manifestations of acute and chronic hepatic porphyrias. After excessive alcohol infestion in man a secondary hepatic coproporphyrinuria develops transiently, which persists in alcoholic liver disease. The alcohol-liver-porphyrinuria syndrome ranges first among the secondary hepatic disturbances of porphyrin metabolism. In acute hepatic porphyrias (acute intermittent porphyria, porphyria varigata and hereditary coproporphyria) alcohol induces delta-aminolevulinic acid synthase because in these porphyrias the control mechanisms of porphyrinogen and heme synthesis in liver are disturbed ("molecular regulatory diseases"). On the contrary, in chronic hepatic porphyrias, which are already associated with liver damage ("membrane diseases"), alcohol potentiates the disturbance of the decarboxylation of uro- and heptacarboxyporphyrinogen, which is followed by a hepatic accumulation of uro- and heptacarboxyporphyrin and their sometimes extreme urinary excretion. Alcohol may transform a symptomatic coproporphyrinuria into chronic hepatic porphyria. One can deduct from experimental and clinical studies that in liver alcohol inhibits the enzymes coproporphyrinogen oxidase, delta-aminolevulinic acid dehydratase and uroporphyrinogen decarboxylase and induces delta-aminolevulinic acid synthase. Abstinence from alcohol is an important measure in the therapy and prophylaxis of all hepatic porphyrias.
    Digital Access Access Options