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  • Book
    [edited by] Terry L. Schwinghammer, Joseph T. DiPiro, Vicki L. Ellingrod, Cecily V. DiPiro.
    Summary: Pharmacotherapy Handbook, Eleventh Edition delivers quick-access answers in any clinical setting. Whether you're a student, pharmacist, and hospital administrator, it offers a thorough understanding about what drugs are used in various situations, and why. The text delivers both the key points pharmacists needs to know in practice and the information students studying for the boards needs to pass. With JNC-VI guidelines-- the standard for drug therapy and pharmaceutical care--it facilitates fast and easy access to answers, and all text will appear on AccessPharmacy for the first time.

    Contents:
    Bone and Joint disorders
    Cardiovascular disorders
    Dermatologic disorders
    Endocrinologic disorders
    Gastrointestinal disorders
    Gynecologic and Obstetric disorders
    Hematologic disorders
    Infectious Diseases
    Neurologic disorders
    Nutrition Support
    Oncologic disorders
    Ophthalmic disorders
    Psychiatric disorders
    Renal disorders
    Respiratory disorders
    Urologic disorders.
    Digital Access AccessPharmacy 2021
  • Article
    Lavine RL, Brodsky I, Garofano CD, Rose LI.
    Diabetologia. 1978 Aug;15(2):113-6.
    To study the effect of E. Coli L-asparaginase on glucose tolerance and insulin release, 6 patients with neoplastic disease were subjected to 3 hour oral glucose tolerance tests with simultaneous measurement of serum immunoreactive insulin (IRI) levels before and following the intravenous administration of 5000 I. U. L-asparaginase/day for 4 days. Five of the patients exhibited a significant deterioration in glucose tolerance; however, no change was noted in their fasting glucose and IRI levels. The deterioration in glucose tolerance was associated with a decrease in the amount of insulin secreted in the first 30 minutes after the oral glucose load. The total amount of insulin released during the 3 hour test remained unchanged. These studies suggest that L-asparaginase can cause a deterioration of glucose tolerance without accompanying fasting hyperglycaemia. This may be due, in part, to a decrease in glucose-induced insulin release during the first thirty minutes following oral glucose.
    Digital Access Access Options