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- ArticleWein AJ, Hanno PM, Raezer DM, Benson GS.Urology. 1978 Aug;12(2):184-6.A double-blind study of the short-term effects of oxybutynin chloride versus placebo on bladder spasm after transurethral surgery was done in 106 male patients. No significant difference between the placebo and 10 mg. or 20 mg. of the drug was noted.