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  • Book
    Giovanni Landoni, Martina Baiardo Redaelli, Chiara Sartini, Alberto Zangrillo, Rinaldo Bellomo, editors.
    Summary: The 2nd edition of this book describes the recent techniques, strategies, and drugs that have been demonstrated by multicenter randomized trials to influence survival in critically ill, defined as those who have acute failure of at least one organ, due to either a pathological condition or a medical intervention, and require intensive care treatment. Each chapter focuses on a specific procedure, device, or drug. The scope is accordingly wide, with coverage of topics as diverse as noninvasive mechanical ventilation, protective ventilation, prone positioning, intravenous salbutamol in ARDS, high-frequency oscillatory ventilation, mild hypothermia after cardiac arrest, daily interruption of sedatives, tranexamic acid, diaspirin cross-linked hemoglobin, albumin, growth hormone, glutamine supplementation, tight glucose control, supranormal oxygen delivery, and hydroxyethyl starch in sepsis. The topics selection was performed with the help of hundreds of specialists from dozens of countries; they expressed via web if they agreed or not with these topics and if they used them in their daily clinical practice. The clear text is supported by "how to do" sections and "key point" boxes that provide easily accessible practical information. Written by acknowledged international experts, Reducing Mortality in Critically Ill Patients is of interest for a wide variety of specialists, including intensivists, emergency doctors, and anesthesiologists.

    Contents:
    The process of consensus building
    Non-invasive ventilation
    High Flow Nasal Cannulae
    Restrictive inspiratory oxygen fraction
    Mechanical ventilation
    Early tracheostomy
    Pharmacological Managment of cardiac arrest
    Non pharmacological Managment of cardiac arrest
    Avoidance of deep sedation
    Hydrocortisone in sepsis; Goal directed therapy
    Levosimendan in cardiogenic shock and low cardiac output syndrome
    Drugs in myocardial infarction
    Tranexamic acid in trauma patients
    Procalcitonin-guided antibiotic discontinuation
    Selective decontamination of digestive tract
    Nutrition
    ECMO
    Ultrasound
    Alternative medicine
    Interventions increasing mortality
    Conflicting
    Latest evidences.
    Digital Access Springer 2021
  • Article
    Cooper BH, Johnson JB, Thaxton ES.
    J Clin Microbiol. 1978 Apr;7(4):349-55.
    The results of over 400 tests for identification of clinical yeast isolates as to species using the Uni-Yeast-Tek (UYT) system in comparison with a more conventional system are reported. The conventional system utilized a total of 23 individual tests, including both fermentation and assimilation tests, whereas the UYT system included only 11 separate tests. In the initial phase of the study, coded unknown isolates were evaluated by each of two technologists using both methods independently. After this initial evaluation, the two methods were used in parallel for routine testing of yeast isolates as they were obtained from clinical specimens. A further evaluation of the UYT system was carried out by retrospectively analyzing the species reported from a clinical mycology laboratory during two separate time periods in which different approaches to yeast identification were employed. A total of 92% of the isolates tested with the UYT system were correctly reported within 72 h, 96% were correctly named after 1 week of incubation, and 97% were correctly reported after 2 weeks of incubation of UYT plates at 30 degrees C when results of the two phases of the study were analyzed together. With the conventional system, 88% of the isolates were correctly reported at 72 h, 96% at 1 week, and 98% after 2 weeks of incubation of biochemical tests. Retrospective analysis of laboratory records revealed no major changes in species reported after adoption of the UYT system for routine testing of clinical isolates. The data presented in this report suggest that the UYT system can be expected to yield rapid presumptive identification of clinical yeast isolates with reasonable confidence when certain minor limitations that are discussed in the text are taken into account.
    Digital Access Access Options