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  • Book
    Malgorzata Kloc, editor.
    Summary: This volume presents a comprehensive overview of the latest developments in symbiosis research. It covers molecular, organellar, cellular, immunologic, genetic and evolutionary aspects of symbiotic interactions in humans and other model systems. The book also highlights new approaches to interdisciplinary research and therapeutic applications. Symbiosis refers to any mutually beneficial interaction between different organisms. The symbiotic origin of cellular organelles and the exchange of genetic material between hosts and their bacterial and viral symbionts have helped shaped the current diversity of life. Recently, symbiosis has gained a new level of recognition, due to the realization that all organisms function as a holobiome and that any kind of interference with the hosts influences their symbionts and vice versa, and can have profound consequences for the survival of both. For example, in humans, the microbiome, i.e., the entirety of all the microorganisms living in association with the intestines, oral cavity, urogenital system and skin, is partially inherited during pregnancy and influences the maturation and functioning of the human immune system, protects against pathogens and regulates metabolism. Symbionts also regulate cancer development, wound healing, tissue regeneration and stem cell function. The medical applications of this new realization are vast and largely uncharted. The composition and robustness of human symbionts could make them a valuable diagnostic tool for predicting impending diseases, and the manipulation of symbionts could yield new strategies for the treatment of incurable diseases.

    Contents:
    Part 1. Transfer of genetic information, nuclear symbiosis, and cellular differentiation
    1. Viral Symbiosis in the Origins and Evolution of Life with a Particular Focus on the Placental Mammals
    2. Gene Transfer Agents in Symbiotic Microbes
    3. Evolution from free-living bacteria to endosymbionts of insects: genomic changes and the importance of the chaperonin GroEL
    4. Epidemiology of nucleus-dwelling Holospora: infection, transmission, adaptation, and interaction with Paramecium
    5. Trends in symbiont-induced host cellular differentiation
    Part 2. Origin, adaptations and evolutionary aspects of symbiosis
    6. We're in this together: Sensation of the host cell environment by endosymbiotic bacteria
    7. Phenotype Heritability in Holobionts: An Evolutionary Model
    8. The role of constructive neutral evolution in the development of complexity from symbioses: A microbe-centric view
    9. Chemiosmosis, evolutionary conflict, and eukaryotic symbiosis
    10. Symbiotic origin of apoptosis
    11. The puzzling conservation and diversification of lipid droplets from bacteria to eukaryotes
    Part 3. Evolution and role of symbiosis in photosynthesis and nitrogen fixation
    12. Evolution of Photosynthetic Eukaryotes; Current Opinion, Perplexity and a New Perspective
    13. The photosynthetic adventure of Paulinella spp
    14. The evolutionary aspects of legume nitrogen-fixing nodule symbiosis
    15. Early molecular dialogue between legumes and rhizobia: why are they so important?
    Part 4. Diversity of nematode and insect symbionts
    16. The Wolbachia Symbiont: Here, There and Everywhere
    17. The Wolbachia Symbiont: Here, There and Everywhere
    18. The Diversity of Symbiotic Systems in Scale Insects
    19. Bacterial Symbionts of Tsetse Flies: Relationships and Functional Interactions between Tsetse and their Symbionts
    Part 5. Symbiosis, adaptive and immune responses, and therapeutic interventions
    20. Our microbiome: on the challenges, promises, and hype
    21. Endosymbiont-mediated adaptive responses to stress in holobionts
    22. Microbial Metabolites as Molecular Mediators of Host-Microbe Symbiosis in Colorectal Cancer
    23. The macrophages and intestinal symbiosis.
    Digital Access Springer 2020
    Access via Results and problems in cell differentiation ; 2020; 69.
    Location
    Version
    Call Number
    Items
    Results and problems in cell differentiation ; 2020; 69.
    2020
    QH607 .R4 v.69 2020
  • Article
    Shimamura T, Cotton J, Wang JC.
    Exp Mol Pathol. 1978 Oct;29(2):253-9.
    Digital Access Access Options