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  • Book
    Deborah F. MacFarlane, editor.
    Summary: The incidence of skin cancer continues to rise, as do the challenges physicians face in treating the growing population of skin cancer patients. Skin Cancer Management: A Practical Approach, 2nd edition addresses the spectrum of skin cancers from the precancerous to the inoperable. In this revised and updated edition, a wide selection of medical treatments and surgical procedures are described in detail and supplemented with an abundance of full-color figures. Numerous case studies help to illustrate the various techniques. .

    Contents:
    Biopsy Techniques and Interpretation
    Topical Therapies for Nonmelanoma Skin Cancers
    Chemical Peels for Precancerous Skin Lesions
    Photodynamic Therapy
    Intralesional and Perilesional Treatment of Skin Cancers
    Electrodesiccation and Curettage
    Cryosurgery
    Optimizing Surgical Outcomes
    Anxiolysis, Anesthesia, and Analgesia
    Excision Techniques and Materials
    Mohs Surgery
    Principles of Cutaneous Flap Surgery
    Techniques in Skin Grafting
    Nail Surgery and Malignant Tumors of the Nail Unit
    Practical Management of Melanoma
    Skin Cancer in Skin of Color
    Management of Skin Cancers in Solid Organ Transplant Recipients
    Imaging of Head and Neck Skin Cancer
    Radiation Oncology in Skin Cancer Treatment
    When to Refer Out
    Chemoprevention of Keratinocyte Carcinomas
    Systemic Therapy for Locally Advanced and Metastatic Non-Melanoma Skin Cancer.
    Digital Access Springer 2021
  • Article
    Rao PS, Marino BL, Robertson AF.
    Arch Dis Child. 1978 Jun;53(6):456-60.
    Differential diagnosis of cyanosis in the neonate is difficult and cardiac catheterisation may be required for a correct diagnosis. It has been suggested that the response of PaO2 to continuous positive airway pressure (CPAP) with 100% oxygen may be useful. The purpose of this study was to test further this hypothesis by studying all neonates investigated for cyanosis with a PaO2 less than or equal to 50 torr in 0-8 to 1-0 F1O2. Arterial blood samples were obtained in an F1O2 of 0-21-0-4 and 0-8-1-0, and in an F1O2 of 0-8-1-0 with 8-10 cm CPAP, and were analysed for PaO2, PaCO2, and pH, bicarbonate being calculated. The final diagnoses were congenital heart disease (CHD) 21 cases, pulmonary parenchymal disease (PD) 10 cases, and persistent fetal circulation (PFC) 3 cases. No significant difference in pH, bicarbonate, or PaCO2 was observed among the three groups or with CPAP. In the CHD and PFC infants CPAP produced no significant change in PaO2. In the PD babies PaO2 increased by an average of 33 torr (P less than 0-05). Despite thus attaining statistical significance 2 PD infants had no increase in PaO2 with CPAP. An increase of PaO2 greater than 10 torr with CPAP suggests PD, and a nonsignificant increase in PaO2 does not rule out PD. Irrespective of initial PaO2, final PaO2 in 0-8-1-0 F1O2 with CPAP greater than 50 torr suggests PD, and less than 50 torr suggests CHD. The results indicate that CPAP may be used as an adjunct in differentiating cardiac from pulmonary disease.
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