Today's Hours: 8:00am - 6:00pm
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Book
    Methil Kannan Kutty, Asita Elengoe, editors.
    Summary: This book summarizes the effects of obesity on health and its correlation with a wide range of debilitating and life-threatening conditions in humans. It discusses the possible pathological mechanisms that are involved in the development of obesity and highlights obesity-associated molecular mechanisms that contribute to reproductive dysfunctions in men and women. The book provides mechanistic insights on the role of obesity in cardiovascular and respiratory disorders, and examines the role of the complementary molecular mechanism of the gut microbiota in the development of obesity. It also reviews the interaction between the metabolic system and immune cells in the pathogenesis of obesity-associated diseases. Lastly, it assesses the latest advances in nanomedicine as an emerging strategy for the treatment of obesity.

    Contents:
    Chapter 1. Introduction
    Chapter 2. The Economics of Obesity-A Public Policy Perspective
    Chapter 3. Obesity and skin problems
    Chapter 4. Obesity and endometriosis
    Chapter 5. Hypogonadism
    Chapter 6. Effect of obesity in cardiovascular system
    Chapter 7. Impact of obesity on vaccination
    Chapter 8. Obesity-linked diseases (Comorbidities)
    Chapter 9. Imaging as a tool for measuring body fat
    Chapter 10. Extrapolation from clinical trial to practice: current pharmacotherapy on obesity
    Chapter 11. Nanotechnology in the context of obesity
    Chapter 12. Computational approach in drug development for obesity.
    Digital Access Springer 2021
  • Article
    Jackson RT, Harris LF, Alford RH.
    Antimicrob Agents Chemother. 1978 Jul;14(1):118-25.
    Plasmid-carrying Klebsiella pneunomiae clinical isolates with agar dilution minimum inhibitory concentrations (MIC) of 32 mug/ml or greater were tested for in vitro potentiation of cephalothin activity by clavulanic acid (BRL-14151), an inhibitor of beta-lactamases. The addition of 10 mug of clavulanate per ml caused greater than a 500-fold reduction in geometric mean cephalothin agar dilution MIC, with lesser but significant reductions resulting from clavulanate concentrations of 5 or 1 mug/ml. Clavulanate-potentiated reduction of cephalothin MICs in broth against resistant Klebsiella were comparable to reduction in agar dilution MICs as a rule. However, a low concentration (1 mug/ml) of clavulanate produced cephalothin MICs in broth several-fold higher than by the agar dilution method. Modest cephalothin-potentiating effects of clavulanate on cephalothin-susceptible strains and on cefoxitin against cephalothin-resistant Klebsiella strongly suggested that the major effect of clavulanate was beta-lactamase inhibition.
    Digital Access Access Options